Epilepsy

Question 1

therapeutic action Barbiturates

Answer 1

epilepsy

Question 2

mechanism of action Barbiturates

Answer 2

non-selective reduction of the CNS via an increase in neurotransmitters that use GABA receptors as a blocking system.

They can lower excitatory neurotransmitter results, which lowers the need for alertness and wakefulness > anaesthetic

Question 3

adverse reactions Barbiturates

Answer 3

confusion
sedation
abnormal thinking

Question 4

contraindications Barbiturates

Answer 4

elderly patients

debilitated patients

Question 5

drug interaction Barbiturates

Answer 5

alcohol

Question 6

therapeutic action Phenytoin

Answer 6

Seizures

Question 7

mechanism of action Phenytoin

Answer 7

phenytoin inhibits voltage gated sodium channels, hereby reducing the multiplication of seizures.

Question 8

adverse reactions Phenytoin

Answer 8

drowsiness
acne
blurred vision

Question 9

contraindications Phenytoin

Answer 9

pregnancy

liver impairment

Question 10

drug interaction Phenytoin

Answer 10

Warfarin

Question 11

therapeutic action Gabapentin

Answer 11

neuropathic pain

Question 12

mechanism of action Gabapentin

Answer 12

Gabapentin interferes with the calcium channels in the neurotransmitter, and hereby reduces the discharge of miscellaneous transmitters.

Question 13

adverse reactions Gabapentin

Answer 13

tremor
nausea
anxiety

Question 14

contraindications Gabapentin

Answer 14

renal impairment

haemodialysis > dialyse

Question 15

drug interaction Gabapentin

Answer 15

morphine

Question 16

therapeutic action Sodium Valproate

Answer 16

Bipolar

Question 17

mechanism of action Sodium Valproate

Answer 17

possible impairment of K+, Ca2+ and N+ channels and GABA reuptake

Question 18

adverse reactions Sodium Valproate

Answer 18

tremor
hair thinning
hepatoxicity

Question 19

contraindications Sodium Valproate

Answer 19

liver disease

pregnancy

Question 20

drug interaction Sodium Valproate

Answer 20

aspirin