autonomic nervous system Flashcards

1
Q

therapeutic action Adrenaline

A

emergency treatment anaphylactic shock

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2
Q

mechanism of action Adrenaline

A

both alpha- and beta-receptors are activated by adrenaline, but the main functions are the beta-receptors of the bronchi, blood vessels, heart and smooth muscle.

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3
Q

adverse effects Adrenaline

A

hyperactivity
arrhytmias
insomnia

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4
Q

contraindications Adrenaline

A

hypoxia (body is deprived of oxygen supply at the tissue level)

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5
Q

drug interaction Adrenaline

A

atherosclerosis

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6
Q

therapeutic action a1-selective antagonist (prazosin)

A

hypertension

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7
Q

mechanism of action a1-selective antagonist (prazosin)

A

selective barrier

decreased peripheral vascular resistance is caused by a selective barrier of post-synaptic a1-receptors, caused by impairment of vasoconstriction set in motion by catecholamine.
This causes a slight increase in heart rate

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8
Q

adverse effects a1-selective antagonist (prazosin)

A

dizziness
headache
fatigue

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9
Q

contraindications a1-selective antagonist (prazosin)

A

renal disease

liver disease

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10
Q

drug interaction a1-selective antagonist (prazosin)

A

beta-blockers

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11
Q

therapeutic action beta-blockers (propranolol)

A

hypertension

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12
Q

mechanism of action beta-blockers (propranolol)

A

catecholamine actions are competitively blocked due to the impairment of B-receptors.
It has both metabolic and cardiac effects

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13
Q

adverse effects beta-blockers (propranolol)

A

insomnia
fatigue
nightmares

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14
Q

contraindications beta-blockers (propranolol)

A

asthma

bradycardia

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15
Q

drug interaction beta-blockers (propranolol)

A

antacids

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