anti-inflammatories Flashcards
1
Q
Therapeutic action Aspirin
A
Headache
2
Q
Mechanism of action Aspirin
A
Irreversibly impairs COX activity, causing a steric hindrance, prohibiting the metabolization of arachadonic acid.
3
Q
adverse effect Aspirin
A
GIT-distress
Allergic reactions
Renal damage
4
Q
contraindications Aspirin
A
Renal impairment
Asthma
5
Q
drug interaction Aspirin
A
Warfarin
6
Q
Therapeutic use Paracetamol
A
Fever
7
Q
Mechanism of action Paracetamol
A
Unknown
Synthesis of prostaglandin gets impaired within the CNS
8
Q
adverse effect Paracetamol
A
overdosis between 20-30 tablets causes severe liver damage
50+ tablets lead to death, unless ACETYLCYSTEINE is administered
9
Q
contraindications Paracetamol
A
pregnancy
glaucoma
10
Q
drug interaction Paracetamol
A
Warfarin
