menopause Flashcards
1
Q
therapeutic actions biphosphonates
A
postmenopausal osteoporosis
2
Q
mechanism of action biphosphonates
A
decreases fracture rate and increases bone mineral density due to the binding of biphosphonates to mineralised bone.
powerful suppressors of osteoclastic-mediated bone erosion and resorption.
3
Q
adverse effects biphosphonates
A
headache
rash
osteomalacia (softening of bones)
4
Q
contraindications biphosphonates
A
osteomalacia (softening of bones)
pregnancy
5
Q
drug interaction biphosphonates
A
NSAIDS (non steroidal anti inflammatory drugs)