menopause Flashcards

1
Q

therapeutic actions biphosphonates

A

postmenopausal osteoporosis

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2
Q

mechanism of action biphosphonates

A

decreases fracture rate and increases bone mineral density due to the binding of biphosphonates to mineralised bone.
powerful suppressors of osteoclastic-mediated bone erosion and resorption.

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3
Q

adverse effects biphosphonates

A

headache
rash
osteomalacia (softening of bones)

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4
Q

contraindications biphosphonates

A

osteomalacia (softening of bones)

pregnancy

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5
Q

drug interaction biphosphonates

A

NSAIDS (non steroidal anti inflammatory drugs)

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