calcium channel blockers (amlodipine)

Question 1

Therapeutic use Amlodipine

Answer 1

Hypertension

Question 2

Mechanism of action Amlodipine

Answer 2

lowers blood pressure through vascular smooth muscle relaxation, vasodilation and reduced total peripheral resistance.
It competitively inhibits calcium ion access into cells and therefore decreases the volume of calcium, that is obtainable for the excitation-contraction processes.

Question 3

Adverse effects Amlodipne

Answer 3

headaches
hypotension
dizziness

Question 4

Contraindications Amlodipine

Answer 4

severe aortic stenosis

severe obstructive coronary artery disease

Question 5

Drug interaction Amlodipine

Answer 5

ephedra