Antineoplastic Flashcards

1
Q

therapeutic actions Methotrexate

A

breast cancer

Rheumatoid arthritis

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2
Q

mechanism of action Methotrexate

A

S-phase cell-cycle-specific antimetabolite

Immunosuppressants in autoimmune disorders, such as rheumatoid arthritis

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3
Q

adverse effects Methotrexate

A

bone marrow suppression
immunosuppression
alopecia

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4
Q

contraindications Methotrexate

A

gout

dehydrated patients

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5
Q

drug interactions Methotrexate

A

alcohol

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6
Q

therapeutic actions Anastrozole

A

post menopausal breast cancer

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7
Q

mechanism of action Anastrozole

A

Anastrozole stops the body from producing estrogen, causing the metastatic tumours to die.
By stopping estrogen production, the recurrence risk of these tumours is much smaller.

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