Antivirals

Question 1

mechanism of action Aciclovir

Answer 1

treatment herpes simplex virus

Production of viral DNA gets deactivated

Question 2

mechanism of action Nevirapine

Answer 2

treatment HIV

Blocks DNA-dependent and RNA-dependent DNA- polymerases

Question 3

mechanism of action Abacavir

Answer 3

treatment HIV

Viral RNA gets transformed by the viral reverse transcriptase enzyme, into pro-viral DNA, after which it is incorporated into the host-cell chromosome of susceptible cells

Question 4

mechanism of action Nelfinavir

Answer 4

treatment HIV

Following maturation, the virus gets blocked by a protease inhibitor, through preventing the cleaving from the polypeptide by the protease

Question 5

mechanism of action Enfuvirtide

Answer 5

treatment HIV

GP41 functions as a binding site for the fusion inhibitor, a synthetic 36-amino-acid peptide.
To block viral fusion, the host cells’ CD4 receptor blocks viral function.

Question 6

mechanism of action Oseltamivir

Answer 6

treatment flu virus

On cell surface impairment of neuraminidase enzyme, further hindering the virus from spreading and exiting.