Thrombolytic Agents Flashcards
1
Q
Thrombolytic Agents
Drug Names
A
Alteplase
Reteplase
Tenecteplase
Urokinase
2
Q
Indications
A
Acute MI, pulmonary emboli, ischemic stroke
3
Q
Actions
A
Activating plasminogen to plasmin, which in turn breaks down fibrin threads in a clot to dissolve a formed clot
4
Q
Contraindications
A
Allergy
Any condition that would be worsened by dissolution of clots
Pregnancy
5
Q
Adverse Effects
A
Bleeding
Cardiac arrhythmias
Hypotension
Hypersensitivity: rash, flushing, bronchospasm, and anaphylactic reaction
6
Q
Drug-Drug Interaction
A
Anticoagulants
Antiplatelet