Thrombolytic Agents Flashcards

1
Q

Thrombolytic Agents

Drug Names

A

Alteplase
Reteplase
Tenecteplase
Urokinase

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2
Q

Indications

A

Acute MI, pulmonary emboli, ischemic stroke

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3
Q

Actions

A

Activating plasminogen to plasmin, which in turn breaks down fibrin threads in a clot to dissolve a formed clot

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4
Q

Contraindications

A

Allergy
Any condition that would be worsened by dissolution of clots
Pregnancy

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5
Q

Adverse Effects

A

Bleeding
Cardiac arrhythmias
Hypotension
Hypersensitivity: rash, flushing, bronchospasm, and anaphylactic reaction

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6
Q

Drug-Drug Interaction

A

Anticoagulants

Antiplatelet

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