Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Block 1 Pharmacology > Immune Stimulants > Flashcards

Immune Stimulants Flashcards

1
Q

Immune Stimulants

Sub-Categories

A

Interferons
Interleukins
Colony-stimulating factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Interferons

A

Naturally released from human cells in response to viral invasion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Interleukins

A

Communicate between lymphocytes, stimulate cellular immunity, and inhibit tumor growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Colony-Stimulating Factors

A

Stimulate bone marrow to produce more WBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Interferons: Actions

A

Preventing virus particles from replicating inside other cells
Stimulating interferon receptor sites on noninvaded cells to produce antiviral proteins
Inhibiting tumor growth and replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Interferons: Contraindications

A

Known allergy
Pregnancy/lactation
Use with caution in cardiac disease, myelosuppression, and with CNS dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Interferon: Adverse Effects

A

Lethargy, myalgia, arthralgia, anorexia, nausea, HA, dizziness, bone marrow depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Interferon: Drug-Drug Interactions

A

No reported interactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Interleukins: Types of Preparations

A

Aldesleukin: Human interleukin produced by recombinant DNA technology using Escherichia coli bacteria
Oprelvekin: A newer agent produced by DNA technology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Interleukins: Actions

A

Increase the number of natural killer cells and lymphocytes

Activates cellular immunity and inhibits tumor growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Interleukins: Indications

A

Aldesleukin: Specific renal carcinomas; possible treatment of AIDS and AIDS-related disorders
Oprelvekin: Prevention of severe thrombocytopenia after myelosuppressive chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Interleukins: Contraindications

A

Known allergy

Pregnancy/lactation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Interleukins: Adverse Effects

A

Lethargy, myalgia, arthralgia, fatigue, fever, respiratory difficulties, depression with suicidal ideation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Colony-Stimulating Factors:

Drug Name

A

Filgrastim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Colony-Stimulating Factors: Indications

A

Reduction of the incidence of infections and reduction in time to neutrophil recovery with myelosuppressive chemotherapy, leukemia, bone marrow transplants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Colony-Stimulating Factors: Action

A

Can be used to reduce the incidence of infection in patients with bone marrow suppression, to decrease the neutropenia associated with bone marrow transplants and chemotherapy, and to help in the treatment of various blood-related cancers

17
Q

Colony-Stimulating Factors: Contraindications

A

Allergy to any component of the drug, pregnancy/lactation, renal or hepatic disease, radiation and chemotherapy

18
Q

Colony-Stimulating Factors: Adverse Effects

A

GI related, HA, fatigue, generalized weakness, alopecia and dermatitis, and generalized pain and bone pain

19
Q

Colony-Stimulating Factors: Drug-Drug Interactions

A

Increase in the myeloproliferative effects of sargramostim when combined with lithium or corticosteroids

Block 1 Pharmacology (52 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions