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Block 1 Pharmacology > Disease Modifying Antirheumatic Drugs (DMARDs) > Flashcards

Disease Modifying Antirheumatic Drugs (DMARDs) Flashcards

1
Q

DMARDs

Sub-Category

A

Common Tumor Necrosis Factor (TNF) Blockers

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2
Q

TNF Blockers

Drug Names

A

Adalimumab
Etanercept
Infliximab

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3
Q

Actions

A

Act to decrease the local effects of TNF. a locally released cytokine that can cause the death of tumor cells and stimulate a wide range of proinflammatory activities

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4
Q

Contraindications

A

Cannot be used in anyone with acute infection, cancer, sepsis. tuberculosis, hepatitis, myelosuppression or demyelinating disorders

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5
Q

Adverse Effects

A

Black box warnings about risk of serious to fatal infections and the development of lymphomas and other cancers

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6
Q

Drug-Drug Interactions

A

Immune suppressant drugs and live vaccines

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Block 1 Pharmacology (52 decks)

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