Calcium Channel Blockers Flashcards
1
Q
Calcium Channel Blockers
Drug Names
A
Amlodipine Felodipine Nifedipine Diltiazem Verapamil Nicardipine
2
Q
Indications
A
HTN
3
Q
Mechanism of Action
A
Inhibits the movement of calcium ions across the membranes of cardiac muscle cells, depressing the impulse and leading to slowed conduction, decreased myocardial contactility, and dilation of arterioles, which lowers blood pressure and decreases myocardial oxygen consumption
4
Q
Contraindications
A
Allergy
Pregnancy/lactation
Renal and hepatic dysfunction
Heart block or sick sinus syndrome
5
Q
Adverse Effects
A
r/t effects on cardiac output
CNS effects
GI symptoms
Cardiovascular symptoms
6
Q
Drug-Drug Interactions
A
Cyclosporine
7
Q
Drug-Food Interactions
A
Grapefruit juice
8
Q
Assessment
A
HX: allergy, pregnancy/lactation Heart block, sick sinus syndrome Liver and kidney disease Physical: skin, lung sounds, perfusion, CNS, GI, vitals, ECG Labs: liver and kidney function tests
