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Block 1 Pharmacology > Loop Diuretics > Flashcards

Loop Diuretics Flashcards

1
Q

Loop Diuretics

Drug Names

A

Bumetanide
Furosemide
Torsemide

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2
Q

Indications

A

Acute CHF
Acute pulmonary edema
Edema r/t CHF, renal disease, liver disease
Hypertension

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3
Q

Mechanism of Action

A

Blocks the chloride pump which blocks sodium and chloride reabsorption into circulation
Large amounts of sodium and chloride rich urine is excreted
Significant diuresis
Works quickly

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4
Q

Contraindications

A 
Allergy
Electrolyte depletion
Anuria/severe renal failure
Hepatic coma
Pregnancy/lactation
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5
Q

Adverse Effects

A

Hypokalemia/hypocalcemia
Hyperglycemia
Ototoxicity
Hypotension and dizziness

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6
Q

Drug-Drug Interactions

A

Aminoglycosides or cisplatin
Anticoagulation
Indomethacin, ibuprofen, salicylates, or NSAIDs

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Block 1 Pharmacology (52 decks)

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