the blood Flashcards
what can be transported in blood?
-nutrients
-hormones
-wastes
-body heat
What is the component percentage of blood?
-blood plasma 55%
-red blood cells 45%
what are the function of erythrocytes?
-carry oxygen
shape of erythrocytes
-biconcave discs
cellular structure of erythrocytes
-anucleate (no nucleus)
-few organelles
-lack mitochondria
haemoglobin
-iron bearing protein which binds to oxygen
-haemoglobin molecule can bind 4 oxygen molecules
leukocytes
-crucial in body’s defence against disease
-complete cells, with nucleus and organelles
what are the two types of leukocytes?
-granulocytes
-agranuloctes
granulocytes
-granules in their cytoplasm can be stained
-lobed nuclei
-include neutrophils, eosinophils and basophils
agranulocyte
-lack visible cytoplasmic granules
-nuclei are spherical, oval or kidney-shaped
-include lymphocytes and monocytes
incompatibility of blood between mother and fetus
-results in fetal cyanosis
-resulting from destruction of fetal blood cells
fetal haemoglobin and affinity
-fetal haemoglobin has higher binding to oxygen than haemoglobin produced after birth
when do infants get physiologic jaundice
when the liver is unable to get rid of the breakdown products of haemoglobin fast enough
Haemostasis
-refers to the process of stopping bleeding due to a break in a blood vessel
-driven by platelets- cell fragments
what are blood types based on?
-the presence or absence of two antigens- type A and type B
antibodies and antigens in blood
people have antibodies against antigens that are not in their own blood
what is the process of haemostasis
-vascular spams occur
-platelets plug forms
-coagulation events occur
vascular spams occur
-smooth muscle contracts causing vasoconstriction
platelet plug forms
-injury to lining of vessel exposes collagen fibers; platelets adhere
-platelets release chemicals that make nearby platelets sticky; more platelets are attracted to the area; platelets plug forms
coagulation
-clotting factors present in plasma and released by injured tissue cells interact with Ca2+ in a complex cascade resulting in the production of fibrin
-fibrin forms a mesh that traps red blood cells and platelets, forming the clot