the 10 hallmarks of cancer Flashcards

1
Q

what is the anagram

A

sorry David tumours rave about genomes

animals eat idiotic elephants

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2
Q

what does sorry stand for?

what is the treatment?

A

sustaining proliferative signalling

EGFR inhibitors

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3
Q

what does David stand for

what is the treatment?

A

deregulating cellular epigenetic

Aerobic glycolysis inhibitors

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4
Q

what does tumours stand for?

what is the treatment?

A

Tumour-promoting inflammation

anti-inflammatory drugs

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5
Q

what does rave stand for?

what is the treatment?

A

resisting cell death

proapoptotic BH3 mimetics

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6
Q

what does about stand for

A

activating invasion and metastisis

inhibitors

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7
Q

what does genomes stand for

what is the treatment?

A

genome instability and mutation

PARP inhibitors

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8
Q

How many hallmarks are under the control of circadian rhythm

A

6

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9
Q

what does animals stand for

what is the treatment?

A

avoiding immune destruction

immune activating anti-CTLA4 mAb

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10
Q

what does eat stand for

what is the treatment?

A

evading growth suppressors

cyclin-dependent kinase inhibitors

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11
Q

what does idiotic stand for

what is the treatment?

A

inducing angiogenesis

VEGF signalling inhibitors

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12
Q

what does elephants stand for

what is the treatment?

A

enable replicative immortality

telomerase inhibitors

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13
Q

how many hallmarks are needed to cause cancer

A

6

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