TB Flashcards

1
Q

When can a false positive TB skin test occur?

A

When a patient has received the BCG vaccine

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2
Q

A TST is also called what?

A

A purified protein derivative test

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3
Q

Latent TB Tx

3 possible

A
  1. Isoniazid 300 mg max 900 for 9 months
  2. Rifampin 4 months
  3. INH + rifapentine q wk for 12 wks
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4
Q

What regimen is recommend for HIV, pregnant and children? and for what?

A

INH: 300 mg per day max 900 per dose

9 months for Latent TB

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5
Q

What latent TB regimen is not rec’d for HIV, children < 2 or pregnant women

A

INH and Rifapentine

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6
Q

How to you confirm the Dx of Active TB?

A

Skin test likely means active but need to confirm with a sputum culture AFB stain

Definitive With PCR slow growing

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7
Q

In the intensive phase how long is RIPE therapy

A

8 wks

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8
Q

What is the treatment and durtation for conuation phase

A

2 drugs for 4 months

INH and RIF if susceptible

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9
Q

Drugs that cause QT prolongation Abxs

A

FQs

Macrolides

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10
Q

Drugs that cover atypical organisms? 3

A

Azithro

Doxy

Quinolones

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11
Q

Community Associated MRSA SSTIs drugs 3

A
  1. Bactrim
  2. Doxy
  3. Minocycline
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12
Q

More Severe SSTIs needing IV abx or Hospitalization cover what 2 things? and what are the 3 main drugs?

A
  1. Cover MRSA and Streptococcus
  2. Vanc
  3. Linezolid
  4. Daptomycin
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13
Q

WHen should IV abxs be admin for surgical prophylaxis?

A

Cefazolin and Cefuroxime ( 1hour before surgery)

If using quinolones or Vanc 120 minytes before

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14
Q

Common Cold MCPs 2

Influenza 1

Pharyngitis 2

Sinusitis 7

A
  1. Resp Virus: Rhinovirus and coronavirus
  2. Infuenza
  3. Resp viruses and S. Pyrogenes
  4. Resp viruses, S. Pneumo, H. Flu, M. Mat, staphylococcus, anaerobes, and g (-) rods
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15
Q

First line tc for sinusitis?

A

Amox/clav

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16
Q

Treatmetn for Pharyngitis?

A

PCN, Amox

17
Q

Second line tx for sinusitis failure of first

A

Oral 2nd or 3rg gen cephs + clinda, doxy or Resp FQ

18
Q

Tx duration for pharyngitis?

A

10

5 days for azithro

19
Q

What patients are at risk of IE during dental procedures? 4

A
  1. Prosthetic heart valve or heart valve repair with artificial material
  2. Hx of endo
  3. Heart transplant with abnormal heart valve function
  4. Certain congenital heart defects including heart/lung valve disease
20
Q

Adult prophylaxis regimens for Pts at risk of IE during dental procedure?

3 options

A
  1. Oral: amox 2 g 30-60 min before procedure
  2. Cant take oral: Amp 2 g or cefazolin 1 g
  3. Can take oral but PCN allergy:
    1. Clindamycin 600
    2. Azithro or clarithromycin 500
21
Q

Other drugs besides Ceftriaxone that can be used for primary or secondary prophylaxis of SBP?

A
  1. Bactrim
  2. Cipro
22
Q

Mild to moderate Peritonitis and Cholangitis

What to cover? 6

A
  1. PEK
  2. Anaerobes
  3. Strepto
  4. +- enterococcus
23
Q

Mild to Moderate Peritonitis and Cholangitis

5 possible regimens

A
  1. Cefoxitin
  2. Ertrapenem
  3. Moxi
  4. Cefazolin, cefuroxime or ceftriaxone + metro
  5. Cipro or Levo + metro
24
Q

Severe ICU patients Peritonitis and Cholangitis

What pathogens to cover? 12

A
  1. PEK
  2. CAPES
  3. Pseudomonas
  4. Anaerobes
  5. Strepto
  6. +- enterococcus
25
Q

Impetigo

Honey COmb Crust

First choice

If numerous lesions

A
  1. Mupirocin (Bactroban) ointment
  2. Cover MSSA if systemmic: Cephalexin (Keflex)
26
Q

Cellulitis Non-purulent infections

A

Cephalexin 500 mg QID

27
Q

Absess Perulent Infections

Treatment 2

A

Commly caused by CA-MRSA

Bactrim

Doxy

28
Q

DM Foot infections

G (+) Pathogens

4

G (-) 5

A
  1. S. Aureus Including MRSA
  2. Group A Strepto
  3. Viridan group strep
  4. S. Epidermidis
  5. E. Coli
  6. Klebsiella
  7. Proteus
  8. Enterobacter
  9. Pseudomonas
29
Q

DM foot infections

Anaerobic G(+) 2

Aaerobic G (-) 1

A
  1. Peptostrepto
  2. Clostridium Perfringes
  3. B. Fragilis
30
Q

Duration of treatment of DM foot infections

4 total

A
  1. 7-14
  2. More severe: 2-4 wks
  3. Bone and joint: 4-6 wks
  4. Osteo longer