Missed Anticoag Flashcards
Pradaxa
Notes
What is the antidote?
Formulation notes? 3
How should i be taken?
- Praxbind: Idaruzizumab
- Protect from light and moisture, dispense in orignal container and once open it is good for 4 months
- Swallow whole do not crush, chew, or break open, dont admin through NG tube
What if you miss a dose of pradaxa?
Take immediately unless within 6 hours of next dose
Enzyme info for carbamazepine?
It is an inducer1A2, 2C19, 2C8/9, 3A4
When do you give IV Vit K and four factor?
If the patient has a major bleed from warfarin
How long should VTE treatment be?
If it s reversable cause or surgery treat for 3 months
How do you bridge from enoxaparin to warfarin?
PE tx continue enoxaparin for at least 5 days while on warfarin until INR is stable for 24 hours
How long should warfarin be used when patient has a Fib and is undergoing cardioversion?
3 wks prior and 4 wks after
CHADS2
C: CHF
H: HTN
A: Age >= 75
D; DM
S prior stroke or TIA
>= 2 oral anticoag
Indications for Edoxaban, Apixaban, Rivaroxaban and Dabigatran
- Nonvalvular A fib
- Treatment of DVT and PE
Boxed warning for Oral Factor Xa
- All: pts receiving neuraxal anesthesia (epideral, spinal) or undergong spinal procedure at risk of hematomas and subsequent paralysis
Enoxaparin Black BOx
Pts receiving neuraxial anesthesia (epidural/spinal) or undergoing spinal puncture at risk of hematomas and subsequent paralysis
Admin instructions and SEs of IV Vit K
Anaphylaxis infuse slowly
What is preferred for pts with cancer?
LMWH
How does warfarin work?
Vit K antagonist
Block activation of II, VII, IX, X
Apixaban dosing for TREATMENT of VTE/PE
10 mg PO BID x 7 days
then 5 mg PO BID