ID 11 Flashcards

1
Q

What 3 Abx types are concentration dependent killers

A
  1. AGs
  2. Quinolones
  3. Dapto
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2
Q

What 4 abxs are AUC:MIC dep

A
  1. Vanc
  2. Macrolides
  3. Tetracyclines
  4. Polymyxins
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3
Q

Only PCN active against Pseudomonas?

A

Zosyn

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4
Q

PCN class effects? 2 Cautions and such

A
  1. Avoid in beta-lactam allergy except pregnant patients with syphilis
  2. All PCns increase risk of seizure in renal impairment
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5
Q

Cephalosporins are not active againts?

A

Enterococcus

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6
Q

Oral outpatient cephalosporins? 3

A
  1. Gen Cephalexin
    1. Common uses skin infections with MSSA and strep through
  2. Cefuroxime: Acute otitis media, CAP, sinus infection
  3. CAP, sinus infection
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7
Q

Common uses for cefazolin?

A

Surgical prophylaxis

Parenteral

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8
Q

10 in patient pareneteral cephs

A
  1. 1st gen: Cefazolin
  2. 2nd gen Cefotetan, Cefoxitin
  3. 3rd gen: Ceftriaxone and Cefotaxime
  4. 3rd gen Ceftazidime, 4th gen Cefepime
  5. Ceftolozan/Tazo, Ceftaz/Avibactam
  6. Ceftaroline Only beta lactam active against MRSA
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9
Q

Class effects of Carbapenems? 4

A
  1. All cover ESBL producing organisms
  2. All except ertra cover pseudomonas
  3. Dont use with PCN allergy
  4. Seizure risk with higher doses, renal failure or use of imipenem/cilstatin
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10
Q

All carbapenems dont cover what 5 organisms?

A

Atypicals, VRE, MRSA, C. DIf, Stenotrophomonas

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11
Q

What 3 organisms does ertrapenem not cover?

A

PSeudomonas, Acinetobacter, or Enterococcus

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12
Q

3 common uses of Carbapenems

A
  1. Polymicrobial infections mod severe diabetic foot infections
  2. Empiric therapy when resistant organsims are suspected
  3. Resttant pseudomonas or Acinetobacter Not ertra
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13
Q

What monobactam can be used with PCN allergy?

A

Aztreonam

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14
Q

What are the 3 respiratory quinolones?

A

Moxi, levo gemi

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15
Q

8 abxs that do not require renal dose adjustments?

A
  1. Antistaph PCNS (dicloxacillin, nafcillin)
  2. Ceftriaxone
  3. Clindamycin
  4. Doxy
  5. Macrolides (azithro, erythro only)
  6. Metronidazole
  7. Moxi
  8. Linezolid
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16
Q

Cardiac or vascular surgery abx proph 2

A

Cefazolin

Cefuroxime

17
Q

Colorectal suregery abx proph 6 total

A
  1. Cefotetan, cefoxitin, amp/sulbactam, ertra
  2. or Metro or ceftriaxone