Cephs Flashcards

1
Q

What ceph can have increased risk of bleeding and cause a disulfram reaction

A
  • Cefotetan contains a NMTT side chain or which increases bleeding risk and can cause a disulfram rxn
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2
Q

What ceph does not need renal adjustments?

A

Ceftriaxone

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3
Q

What ceph is available in chewable?

A

Cefixime

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4
Q

What ceph covers some CRE bugs?

A

Ceftaz/avibactam

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5
Q

What PCN allergy should you not use cephs with?

A

Type 1 swelling, angioedema, anaphylaxis

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6
Q

Ceftriaxone contraindication?

A

Causes biliary sludging in neonates,

Conccurrent use of Calcium containing IV products in neonates <=28 days

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7
Q

What 4 cephs should be separated by 2 hours with antacids?

A

Cefditoren, cefuroxime, cefpodoxime, cefdinir

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8
Q

First gen cepha coverage?

A

Gram (+) cocci and preferred when using cephs for MSSA

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9
Q

1st gen cephs 2

A

Cefazolin, Cephalexin (Keflex)

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10
Q

Second gen cephs 1

A

Cefuroxime

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11
Q

3rd gen cephs 1

A

Cefdinir

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12
Q

3rd gen group 2: 1

A

Ceftazidime

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13
Q

4 gen cephs

A

Cefepime

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14
Q

5th gen cephs?

A

Ceftaroline (teflaro)

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15
Q

2nd gen cephs what two drugs and what is the added coverage

A

Cefotetan, cefoxitin

Added G (-) anaerobe coverage B. Fragalis

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16
Q

Cefuroxime coverage 7 total

A

Staph and more resistant strains of S. Pneumo

Plus HNPEK

17
Q

3rd gen group 1 coverage and drugs

A

Ceftriaxone and Cefotaxime

  • which cover more resistant strains of strep and
  • veridans group strep,
  • MSSA
  • G (+) anaerobes mouth flora and more resitant strains of HNPEK
18
Q

Ceftazidime coverage?

A

Not active against g(+) but is active against pseudomonas

19
Q

Fourth gen drug and coverage?

A

Cefepime, broad g (-) bacteria HNPEK, CAPES and Pseudomonas

20
Q

Only Beta-lactam that covers MRSA?

A

Ceftaroline