Required Formulas Flashcards
Nonsterile compounding
MWQ
Minimum weighable quantity
Sensitivity requirements/0.05
IBW males and females
IBW males= 50 + 2.3 *(inches over 5 ft)
IBW females = 45.5 + 2.3 (inches over 5ft)
Phenytoin corretion for hypoalbuminuria?
Can also be used for valproic acid
Total phenytoin measured /[(0.2 x albumin) +0.1]
Elimination rate constant
Cl/Vd
meter (m) = centimeters
100 cm
Sensitivity and Specificity
- Test Result Have Condition Dont Have
- Positive A B
- Negative C D
- Total A + C B+D
- Sensitivity=A/(A+C)x 100
- Specificity= D/(B+D) x 100
BMI
weight in kg/height m^2
Total energy expenditure TEE
BEE * activity factor * stress factor
tsp=ml
5 mL
1 oz = grams
28.4 g
mEq
(mg * valence)/MW
OR
mmols * valence
Calcium _____: __ % elemental
Calcium ____ ___
Carbonate 40%
Citrate 21%
BSA calculation oncology
BSA m2= Sqrt (ht(cmx wt(kg)/3600
Celsius to fahrenheit
(F-32)/1.8
C*1.8 + 32
NNT or NNH-
1/ARR(expressed as a decimal)
How to determine fluid requirements
if > 20 kg
1,500 mL + (20 mL) (wt in kg -20)
Osmolarity
mOsmol/L
= Wt of substance in (g/L) / MW (g/mole) * # of particles * 1000
Absolute neutrophil count (ANC) (cells/mm3)
WBC x [(%segs +%bands)/100]
tbsp=mL
15 mL
Loading Dose (LD)
(Desired concentrations * Vd) / F
Biostatistics:
Relative Risk
Risk=?
Relative Risk=?
Risk= Number of subjects with unfavorable event in group/ total number of subjects in group
RR= Risk in treatment group/ risk in control group
TTB time to burn
TTB ( with sunscreen in min)= SPF x TTB (without sunscreen)
Relative Risk Reduction:
(% risk in control group-% risk in treatment group)/ % risk in control group
Cockcroft gault
CrCl= 140-age/(72*Scr) *wt * (0.85 if female)
Grams of nitrogen from protein
protein intake/ 6.25
1 kg= __lbs
2.2lbs
Dilutions and concentrations
Q1 x C1= Q2 x C2
Q1=old quantity
C1= old concentration
Percent ionization
weak acid and weak base
pH= pKa + log (salt/acid)
weak base: pH=pKa + log (base/salt)
1 oz=mL
30 mL
t1/2
0.693/Ke
Moles or Millimoles
mols=g/MW
mmols= mg/MW
1 gallon= __ quarts = __ mL
4 quarts, 3840 mL
Parts per million (PPM)
PPM–> percentage strength
Percentage strength to PPM
Move 4 decimals to the left
Move 4 decimals to the right
Anion gap
= Na- Cl- HCO3
Chronic heart failure loop diuretic dose conversions:
Ethacrynic acid: 50
Furosemide: 40
Torsemide: 20
Bumetanide: 1
Furosemide IV:PO, 1:2
all others 1:1
Diabetes
Insulin to carb ratio
Rule of 500 (with rapid acting)
Rule of 450 with regular
500/total daily dose of insulin(TDD)= grams of carbs covered by 1 unit of rapid acting insulin
450/TDD
1,800/TDD= correction factor
1 pint=oz=mL
16 oz, 480 mL
Clearance
(Fxdose)/AUC or
ke * Vd
Specific gravity
= g/mL
AdjBW
= IBW + 0.4(TBW-IBW)
1 grain= mg
65 mg
ARR Absolute risk reduction:
% risk in control group - (% risk in treatment group)
Steroid dose conversions
8 total
- Cortisone: 25 mg
- Hydrocortisone 20 mg
- Prednisone 5 mg
- Prednisolone 5 mg
- Methylprednisolone 4 mg
- Triamcinolone 4 mg
- Dexamethasone 0.75 mg
- Betamethasone 0.6 mg
Percentage strength=
Ratio strength=
100/ratio strength
100/percentage strength
1 cup=oz=mL
8 oz, 240 mL
Parenteral nutrition calorie levels
Dextrose: 3.4 kcal/g
AA: 4 kcal/g
IV fat 10%: 1.1 kcal/mL
20%: 2 kcal/mL
30%: 3 kcal/mL
ABG: /,/,/
pH acidosis vs. Alkalosis
Respiratory vs Metabolic
pH/pCO2/pO2/HCO3/O2 sat
pH<7.35 acid
>7.45 alkalosis
Res: CO2 <35 alk >45 acid
Metabolic: HCO3 > 26 alkalosis, <22 acidosis
Bioavailability
F(%)= 100 x (AUC extravascular/ AUC intravenous) * (Dose intravenous/dose extracellular)
Isotonicity: E
58.5 (i)/ MW of drug*(1.8)
Odd Ratio:
AD/BC
LDL calculation
TC-HDL - (TG/5)
DOnt use TG if >400
Alligations
High Low-desired=parts high
Desired
Low
When do you know if someone is dehydrated?
BUN:SCr >20:1
HR?
Hazards Ratio
Hazard Rate in Treatment group/ Hazard rate in control group
1 lbs= grams
454 g
1 quart = _ pints = __ mL
2 pints, 960 mL
Inches=centimeters
2.54 cm
Flow rates:
Drops per minute
of drops/mLx mL/hr x hr/60 min = # drops/minute
Volume of Distribution?
Vd= Amount of drug in body/concentration of drug in plasma
percentage strengths
%w/v, w/w and v/v
xg/100mL, xg/100g, x mL/100 mL
Corrected calcium=
Cacorrected (mg/dL)= Reported Calcium +[(4.0 - albumin) x (0.8)]
Regular Insulin Correction Factor
1500/(Total daily insulin)
Correction factor for rapid insulin?
1800/TDD
Correction Dose for insulin?
(BG now)-Target/(Correction factor)
Pharmacists Rock At Saving Lifes and Preventing Flu
Pita: 2 mg
Rosuvastatin: 5
Atorvastatin: 10
Simvastatin: 20
Lova: 40
Pravastatin: 40
Fluvastatin: 80
Modified % ionization for henderson
= 100/(1+10^(pKa-pH))
Novolog, Fiasp
Insulin Aspart
Humalog
Lispro
Humulin R, Novolin R
Regular
Humulin R U-500
Concentrated reg
Humulin N, Novolin N
NPH
Levermir
Determir
Lantus, Toujeo
Glargine
Tresiba
Degludec
Ferrous gluconate
12%
Ferrous Sulfate
20%
Dried Ferrous sulfate
30%
Ferrous Fumurate
33%
Carbonyl Iron
100%
Polysaccarharide iron complex
100%
Ferrous sulfate 325 mg tablet
How much elemental iron?
65
Ferrous sulfate dried
ER
160 mg tablet
50 mg elemental iron