BIO stats Flashcards
Continuos data what are the types and the differences of each and examples/
Interval and Ratio
Ratio has a meaningful zero age, ht, wt
Interval no meaningful zero, celsius (equal distance between values)
Discrete data is also referred to as?
What are the different types and examples of them?
Nominal: Order is arbitrary (gender, ethnicity)
Ordinal ranked in logical order pain scale 0,10
The mean is preferred for what type of data?
continuos and normally distributed data
What is the mean preferred for?
preferred for ordinal or continuous data that is skewed
The mode is preferred for what data?
nominal
Continuous data tends to follow what?
A normal distribution
68% fall within how many?
95%?
within 1 SD
within 2 SDs
When is skewed data likely to occur?
If sample size is small and or there are outliers
What is the best measure of central tendency when you have outliers?
How can the distortion of outliers be reduced?
Median is the best judge
Distortion can be reduced with increased sample size
Right and left skew?
low values to the right positive right skew
left, negative left skew
If the alpha is 5% what does the p-value need to be to reject the null hypothesis?
Confidence interval =?
CI=1- alpha
When are the results statistically significant?
Is there a difference with ratio data? (RR, OR, HR)
If the confidence interval doesnt include zero
Statistically significant if values CI does not contain 1
What is a type 1 error?
Rejecting the null when the null is true
saying there is a difference when there is none
p value correlated to probability of type 1
Type 2?
Accepting the null when the null is false (b)
What is power?
the probability that the test will reject the null hypothesis correctly
How is power calculated?
1-B
why is absolute risk reduction more useful?
because it includes the reduction in risk and the incidence rate
ARR of 12% in metoprolol vs placebo trial what does it mean?
means 12% out of every 100 pts benefited from tx
How do you round NNT?
NNH?
When do you use absolute value?
52.1 round to 53
NNH: 41.9 round down to 41
When calculating NNH use ARR absolute vlue
What kind of studies use odd ratio instead of relative risk?
How do you calculate OR?
Case-controlled studies
OR= AD/BC
When are hazard ratios used?
survival analysis (analysis of death or disease progression)
HR and OR interpretation?
If OR or HR = 1 the event rate is the same
> 1 event rate is higher in treatment group
<1 event rate is lower in tx group