sz bio treatment Flashcards

1
Q

How do the drugs to treat Schizophrenia work?

A

They are psychoactive changing the balance of neurotransmitters in the brain

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2
Q

What neurotransmitters particularly do the anti-psychotics effect?

A

They lower the levels of Dopamine in the synapse

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3
Q

How do the anti-psychotics work?

A

They block the receptor sites meaning there’s less activity at the synapse

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4
Q

How do the anti-psychotics work?

A

They most commonly block the receptor sites meaning there’s less activity in the synapse

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5
Q

What are the two types of antipsychotics?

A

Typical and A-Typical

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6
Q

Why is Clozapine (an atypical) different to other antipsychotics like Haloperidol (a typical)?

A

It blocks less D2 receptors and can also effect other neurotransmitters like Serotonin

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7
Q

What is the first thing a doctor is responsible for with drug treatment?

A

Prescribing the relevant medication

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8
Q

Why would there be follow up meetings with the patient after prescription?

A

Monitoring the patient for side-effects and effectiveness

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9
Q

What happens if the medication isn’t being effective or causes side-effects?

A

Changing medication type and dosage as needed

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10
Q

What is Tardive Dyskinesia

A

A side-effect where you make involuntary muscle movements in the face

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11
Q

What did Meltzer (2004) find?

A

Haloperidol gave significant improvements in all aspects compared to placebo (as did 2 of the other drugs)

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12
Q

What did Emsley find?

A

84% of patients on anti-psychotics had atleast 50% reduction in symptoms if they were given early enough

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13
Q

What did Hogarty find?

A

relapse rates 48% vs 80% without these types of medication

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14
Q

What did Rosa (2005) find?

A

only 50% of patients complied with taking their anti-psychotics.

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15
Q

What did Leiberman (2005) find?

A

Many patients stop taking their medication because of the severe side effects, this effects the effectiveness of this treatment

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16
Q

What did Leucht find?

A

They work better for positive symptoms than negative symptoms

17
Q

What is a major problem with people taking medication?

A

They cause side-effects which are harmful and might stop people taking the medication making it less effective

18
Q

What is a problem if people stop taking the medication

A

They symptoms might return so the medication isn’t long lasting

19
Q

What is a strength of drugs compared to CBT?

A

They are relatively quick acting compared to other treatments like CBT

20
Q

Why might CBT be a better treatment than drugs (pick 2)

A

It is longer lasting as people are taught skills rather than relying on the chemical, It doesn’t cause side-effects and therefore might be a better therapy

21
Q

Which type of symptom is effected more by the medication

A

positive’ symptoms

22
Q

What did Kane (1988) find?

A

200 patients who showed no improvement with the commonly used Haloperidol, 30% responded to Clozapine with an improvement in both positive and negative symptoms