bio explaination of depression Flashcards

1
Q

A neurotransmitter is

A

A chemical which carries messages between nerve cells

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2
Q

What are the names of the group of neurotransmitters linked to depression

A

Monoamines

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3
Q

Which is the main neurotransmitter linked to Schizophrenia?

A

Serotonin

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4
Q

Which neurotransmitter controls the others and is linked to mood and sleep?

A

Serotonin

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5
Q

Which neurotransmitter is linked to enjoyment and concentration?

A

Dopamine

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6
Q

Which neurotransmitter is linked to sleep and mood?

A

Serotonin

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7
Q

Which neurotransmitter is linked to energy levels?

A

Noradrenaline

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8
Q

What are the levels of neurotransmitter/level of activity associated with Depression?

A

Low levels of monoamines

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9
Q

What is an enzyme which breaks down the monoamines in the synapse leading to Depression?

A

MAO

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10
Q

What does MAO have to do with depression?

A

Too much of it means monoamines are broken down too much and there isn’t enough activity at the synapse

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11
Q

Which gene leads to reduced Serotonin production when stressed?

A

5HTT

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12
Q

What did Drevets find?

A

found reduced serotonin receptor-binding potential in unmedicated depressed patients.

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13
Q

What did Angoa-Perez find?

A

found that mice without the gene for tryptophan did not show signs of depression

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14
Q

What did Delgado find?

A

found that low monoamine did not make symptoms worse in depressed patients not taking medication.

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15
Q

What did Versiani find?

A

found that patients who had noradrenaline reuptake inhibitors increased their mood

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16
Q

Why is this a useful theory?

A

It has lead to drug treatments which work to lower symptoms- suggesting that this theory is credible

17
Q

What is a problem in suggesting the drugs ‘prove’ this theory correct?

A

The drugs don’t work for everyone and don’t work instantly despite the fact the drugs change NT level quickly

18
Q

A strength of using NT to explain causes of depression is?

A

Empirical- you can measure neurotransmitters directly

19
Q

What is the problem with saying Monoamines CAUSE depression?

A

It has issues with cause and effect as most of the research is correlational, it could be Depression causes the reduction in monoamines not the other way

20
Q

Why might cognitive be a better explanation?

A

It takes into account the thoughts/cognition i.e. faulty thinking which the neurotransmitter explanation don’t

21
Q

Why is this theory reductionist?

A

It ignores environmental factors like early childhood expereicnes influencing cognitive processes/faulty thinking’s effects

22
Q

What did Bell find?

A

depleted levels of tryptophan and found this caused a relapse of symptoms in depressed patients showing that changing the biology of a person can cause the symptoms of unipolar depression

23
Q

What did Moncrieff (2022) find?

A

The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression