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POD Exam 2 > Streptococcal pyogenes > Flashcards

Streptococcal pyogenes Flashcards

1
Q

Strep Pyogenes is what type of gram bacteria

A

positive

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2
Q

Does it work with or without oxygen

A

facultative anaerobe

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3
Q

Name 2 surface proteins of strep pyogenes

A

M- protein

F-protien

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4
Q

What does M and F proteins help to establish

A

helps establishing infection

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5
Q

opsonization

A

bacteria are targeted for destruction by an immune cell known as a phagocyte

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6
Q

what makes the M protein a virulence factor

A

inhibits opsonization

immunogenic

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7
Q

what makes the F protein a virulence factor

A

mediate adherence to mucoepithelium via binding fibronectin

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8
Q

what makes the C5a peptidase a virulence factor

A

reduces inflammation mediated by C5a

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9
Q

what makes the streptokinase a virulence factor

A

promotes bacterial spread into tissues by breaking down blood clots

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10
Q

what makes the streptolysin O and S a virulence factor

A

lyse RBC by activating plasmin

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11
Q

what is the difference between streptolyisn S and O

A

O: immunogenic
S: nonimmunogenic

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12
Q

What does ASO test for?

A

blood test to measure amount of antibodies against streptolysin O

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13
Q

what makes the DNase a virulence factor

A
  • depolymerizes cell with no nucleus

- aids in bacterial spread

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14
Q

what is Anti-DNase B

A

marker of cutaneous group 1 streptococcal infections

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15
Q

what is the number one causative agent from GAS

A

cellulitis

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16
Q

Erysipelas

A

inflammation of cheeks

17
Q

impetigo

A

crusting with pus

18
Q

when does one get acute glomerular nephritis

A

post presence of Group A streptococcus

  • post-pharyngitis
  • post-skin infection
19
Q

why is there blood in urine for acute glomerular nephritis

A
  • immune complex stuck in basement membrane
  • activates complement
  • bring neutrophils
  • hole in basement membrane
20
Q

why is there facial edema in acute glomerular nephritis

A
  • inflammation
  • scar formation
  • closes fenstrated basement membrane
  • facial edema
21
Q

when does one get acute rheumatic fever

A

post pharyngitis

22
Q

Where is GAS normally found

A

skin and oropharynx

23
Q

what can cause a GAS infection

A

penetration of tissue

24
Q

how is GAS transmitted

A

person to person

25
Q

what is the treatment for GAS

A

Penicillin

-oxacillin or vancomycin (in mixed culture)

26
Q

obligate aerobe

A

requires oxgyen

27
Q

microaerophile

A

reduced oxygen

28
Q

obligate anaerobe

A

no oxygen

29
Q

facultative anaerobe

A

anaerobic or aerobic

30
Q

capnophile

A

require increased CO2

31
Q

alpha hemolytic

A

partial hemolysis

32
Q

beta hemolytic

A

complete hemolysis

33
Q

gama hemolytic

A

no hemolysis

POD Exam 2 (28 decks)

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