Linezolid Flashcards

1
Q

what is the mechanism of action for Linezolid

A

bind to 23S ribosomal RNA of 50S subunit

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2
Q

what is the bio-availbility for PO Linezolid

A

100%

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3
Q

what does Linezolid cover

A

MRSA
VISA
VRE
PCN-resistant strep penumo

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4
Q

what are adverse reactions for Linezolid

A

myelosupression: thrombocytpenia

yeast

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5
Q

what is the drug-drug interaction for Linezolid?

A

MonoAmine Oxidase Inhibitor (MOI)

-SSRI ( serotonin storm)

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