Linezolid Flashcards
1
Q
what is the mechanism of action for Linezolid
A
bind to 23S ribosomal RNA of 50S subunit
2
Q
what is the bio-availbility for PO Linezolid
A
100%
3
Q
what does Linezolid cover
A
MRSA
VISA
VRE
PCN-resistant strep penumo
4
Q
what are adverse reactions for Linezolid
A
myelosupression: thrombocytpenia
yeast
5
Q
what is the drug-drug interaction for Linezolid?
A
MonoAmine Oxidase Inhibitor (MOI)
-SSRI ( serotonin storm)