Chlamydiaceae family Flashcards

1
Q

why are chlamydiacaea family unique

A
  • similar gram (-)
  • DNA /RNA
  • prokaryotic ribosomes
  • susceptible to anitbacterial antibiotics
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2
Q

what is the outer membrane protein for chlamydia tachomatis

A

MOMP

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3
Q

does LGV respond with an immune system

A

no

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4
Q

what type of cells replicate in LVG

A

mononuclear phagocytes

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5
Q

what is the transition zone from cervix to vagina

A

columnar to squamous

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6
Q

what gender gets LGV more frequently

A

men

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7
Q

LGV is a common co-infection with what other disease

A

HIV

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8
Q

Herbert’s pits? what disease does it associte with

A

shallow pits in cornea from form as a result of follicle rupture
-trachoma

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9
Q

how do you made diagnosis for WHO grade TF

A

5 or more white/yellow follicles seen on upper tarsal conjunctivitis

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10
Q

trichiases

A

eyelid conjuctiva scar tissue contracts, distorting lid margin and causing eyelashes to rub on cornea

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11
Q

Pannus

A

growth of vascular tissue over cornea as a result of edema

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12
Q

corneal opacity

A

blurring part of pupil margin

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13
Q

Fitzhugh-curtis syndrome

A

perihepatitis with inflammation of liver capsule

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14
Q

what is the clinical presentation for male urogenital chlamydia

A

urethral discharge or dysuria

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15
Q

how will infant pneumonia show on x-ray

A

bilateral interstitial infiltrates

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16
Q

what is Parinaud oculoglandular syndrome

A

LGV clinical symtpom

conjuctival inflammation with preauricular submandibular and cervical lymphadenopathy

17
Q

what needs to be cultured for chlamydia

A

not pus, vagina

-cervix, rectum, oropharynx

18
Q

Name antigen detection tests for Chlamydia

A

DFA

ELISA

19
Q

how does mycoplasma pnemonia get sterol in cell membrane

A

external source

20
Q

does M. penumoniae need oxygen

A

strict aerobe

21
Q

how does M. pnumonieae attach to cell wall of respiratory tract

A

Terminal adhesion protein ( P1) binds base of cilia of epithelial cells
-loss of ciliated cells

22
Q

what does m. pneumoniae cause in the body

A

stimulates inflammatory cells to site of infection
TNF alpha
IL1
IL6

23
Q

what are clinical symptoms for m. pneumoniae

A
upper respirtory infection
otitis media
tracheobronchitis 
Stevens- Johnson syndrome 
erythema multiforme
24
Q

name 2 lab tests for m. pnumonia

A

seroogy

PCR

25
Q

besides macrolides, what else can help walking pnumonia? who should we not give them

A

tetracyclines fluroquinolones

children