Chlamydiaceae family Flashcards
why are chlamydiacaea family unique
- similar gram (-)
- DNA /RNA
- prokaryotic ribosomes
- susceptible to anitbacterial antibiotics
what is the outer membrane protein for chlamydia tachomatis
MOMP
does LGV respond with an immune system
no
what type of cells replicate in LVG
mononuclear phagocytes
what is the transition zone from cervix to vagina
columnar to squamous
what gender gets LGV more frequently
men
LGV is a common co-infection with what other disease
HIV
Herbert’s pits? what disease does it associte with
shallow pits in cornea from form as a result of follicle rupture
-trachoma
how do you made diagnosis for WHO grade TF
5 or more white/yellow follicles seen on upper tarsal conjunctivitis
trichiases
eyelid conjuctiva scar tissue contracts, distorting lid margin and causing eyelashes to rub on cornea
Pannus
growth of vascular tissue over cornea as a result of edema
corneal opacity
blurring part of pupil margin
Fitzhugh-curtis syndrome
perihepatitis with inflammation of liver capsule
what is the clinical presentation for male urogenital chlamydia
urethral discharge or dysuria
how will infant pneumonia show on x-ray
bilateral interstitial infiltrates
what is Parinaud oculoglandular syndrome
LGV clinical symtpom
conjuctival inflammation with preauricular submandibular and cervical lymphadenopathy
what needs to be cultured for chlamydia
not pus, vagina
-cervix, rectum, oropharynx
Name antigen detection tests for Chlamydia
DFA
ELISA
how does mycoplasma pnemonia get sterol in cell membrane
external source
does M. penumoniae need oxygen
strict aerobe
how does M. pnumonieae attach to cell wall of respiratory tract
Terminal adhesion protein ( P1) binds base of cilia of epithelial cells
-loss of ciliated cells
what does m. pneumoniae cause in the body
stimulates inflammatory cells to site of infection
TNF alpha
IL1
IL6
what are clinical symptoms for m. pneumoniae
upper respirtory infection otitis media tracheobronchitis Stevens- Johnson syndrome erythema multiforme
name 2 lab tests for m. pnumonia
seroogy
PCR
besides macrolides, what else can help walking pnumonia? who should we not give them
tetracyclines fluroquinolones
children
