Allman review

Question 1

what are the gram positive bacteria

Answer 1

staph
strep
enterococcus

Question 2

what are the atypical bacteria

Answer 2

chlamydia
mycoplasma
legionella

Question 3

why are atypical drugs called atypical

Answer 3

they don’t take up red or blue dye, so present atypically

Question 4

what are the anaerobe bugs

Answer 4

peptostreptococcus
bacteroides
clostridium

Question 5

what are the gram negative PIddly drugs

Answer 5

haemophilus
moraxella (M.cat)
salmonella
shigella
morganella

Question 6

what are gram negative bugs that are piddly but also fence bugs

Answer 6

neisseria

providencia

Question 7

why are FENCE bugs called fence bugs

Answer 7

sometimes they are really hard to treat or very easy

Question 8

what is a pan culture

Answer 8

culture everything

blood, urine, sputum

Question 9

what acronym is used for fence bugs

Answer 9

PEK
proteus
E. coli
klebsiella

Question 10

where are SPACE bugs found

Answer 10

hospitals or nursing homes

Question 11

when is broad specturm therapy used

Answer 11

• when we don’t know what the bug is

Question 12

synergy

Answer 12

1+1+5

Question 13

time dependent kill? what is minimum dosing

Answer 13

time above MIC

minimum of 40-50% dosing

Question 14

what do you want in concentration dependent kill

Answer 14

high peak
get post-anti-biotic effect
-10 times MIC for peak

Question 15

Name two dugs that have concentration dependent kill

Answer 15

aminoglycosides

fluroquinolones

Question 16

what are the two penicillins that cover psuedomonas

Answer 16

pipercillin

ticarcylin

Question 17

what cephalosporins cover psuedomonas

Answer 17

4th generation - cepefime
3rd genertaion (antipseudomal) - ceftazidime

Question 18

what does cefoxitin and cefetetan cover

Answer 18

anaerobes

Question 19

which cephalosporin covers MRSA

Answer 19

5th generation: ceftaroline

Question 20

which carbapenems cover pseudomonas

Answer 20

imipenem
meropenim
doripenim

Question 21

MOA fluroquinolones

Answer 21

work on DNA gyrase

Question 22

aminoglycosides MOA

Answer 22

work on 30S

Question 23

what drug is taken orally for gut decontamination

Answer 23

niomyocin

Question 24

Niomyocin high peak has what adverse effect

Answer 24

high ototoxicity

Question 25

Niomyocin too high of troughs is associated with what adverse effect

Answer 25

high nephrotoxicity

Question 26

what other drug beside nicomyosin also exhibits high troughs and high peak side effects

Answer 26

vancomyosin

Question 27

what is the infusion related syndrome with vancyomyocin

Answer 27

Red man’s sydnrome

Question 28

why is methacillin off the market

Answer 28

severe damage to kidneys

interstitial nephritis

Question 29

ampicillin is drug choice for what bacteria

Answer 29

strep
enterococcus
H. flu
salmonella/shigella 
PEK

Question 30

what does aminoglycosides cover

Answer 30

gram (-)

synergy for enterococcus

Question 31

what does vancomycin cover

Answer 31

graph (+) except VRE

MRSA

Question 32

Linezolid covers what

Answer 32

MRSA

VRE

Question 33

what is the drug drug interaction with Linezolid

Answer 33

serotonin uptake inhibitor

causes serotonin storm because it is MOA inhibitor

Question 34

what is Mupricin used for

Answer 34

MRSA eradication

topical only

Question 35

fosfomyocin is good for what type of disease state

Answer 35

UTI