Allman review Flashcards

1
Q

what are the gram positive bacteria

A

staph
strep
enterococcus

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2
Q

what are the atypical bacteria

A

chlamydia
mycoplasma
legionella

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3
Q

why are atypical drugs called atypical

A

they don’t take up red or blue dye, so present atypically

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4
Q

what are the anaerobe bugs

A

peptostreptococcus
bacteroides
clostridium

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5
Q

what are the gram negative PIddly drugs

A
haemophilus
moraxella (M.cat)
salmonella
shigella
morganella
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6
Q

what are gram negative bugs that are piddly but also fence bugs

A

neisseria

providencia

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7
Q

why are FENCE bugs called fence bugs

A

sometimes they are really hard to treat or very easy

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8
Q

what is a pan culture

A

culture everything

blood, urine, sputum

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9
Q

what acronym is used for fence bugs

A

PEK
proteus
E. coli
klebsiella

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10
Q

where are SPACE bugs found

A

hospitals or nursing homes

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11
Q

when is broad specturm therapy used

A
  • when we don’t know what the bug is
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12
Q

synergy

A

1+1+5

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13
Q

time dependent kill? what is minimum dosing

A

time above MIC

minimum of 40-50% dosing

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14
Q

what do you want in concentration dependent kill

A

high peak
get post-anti-biotic effect
-10 times MIC for peak

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15
Q

Name two dugs that have concentration dependent kill

A

aminoglycosides

fluroquinolones

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16
Q

what are the two penicillins that cover psuedomonas

A

pipercillin

ticarcylin

17
Q

what cephalosporins cover psuedomonas

A
4th generation - cepefime
3rd genertaion (antipseudomal) - ceftazidime
18
Q

what does cefoxitin and cefetetan cover

19
Q

which cephalosporin covers MRSA

A

5th generation: ceftaroline

20
Q

which carbapenems cover pseudomonas

A

imipenem
meropenim
doripenim

21
Q

MOA fluroquinolones

A

work on DNA gyrase

22
Q

aminoglycosides MOA

A

work on 30S

23
Q

what drug is taken orally for gut decontamination

24
Q

Niomyocin high peak has what adverse effect

A

high ototoxicity

25
Niomyocin too high of troughs is associated with what adverse effect
high nephrotoxicity
26
what other drug beside nicomyosin also exhibits high troughs and high peak side effects
vancomyosin
27
what is the infusion related syndrome with vancyomyocin
Red man's sydnrome
28
why is methacillin off the market
severe damage to kidneys | interstitial nephritis
29
ampicillin is drug choice for what bacteria
``` strep enterococcus H. flu salmonella/shigella PEK ```
30
what does aminoglycosides cover
gram (-) | synergy for enterococcus
31
what does vancomycin cover
graph (+) except VRE | MRSA
32
Linezolid covers what
MRSA | VRE
33
what is the drug drug interaction with Linezolid
serotonin uptake inhibitor | causes serotonin storm because it is MOA inhibitor
34
what is Mupricin used for
MRSA eradication | topical only
35
fosfomyocin is good for what type of disease state
UTI