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Various Pharm > Skeletal muscle relaxant drugs > Flashcards

Skeletal muscle relaxant drugs Flashcards

1
Q

atracurium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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2
Q

cisatracurium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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3
Q

mivacurium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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4
Q

d-tubocurarine

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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5
Q

pancuronium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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6
Q

pipercuronium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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7
Q

rocuronium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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8
Q

vecuronium

A
  • nondepolarizing blocker of the NMJ
  • prevents access of ACh to its receptor
  • risk of bronchospasm
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9
Q

succinylcholine

A
  • depolarizing blocker of NMJ
  • activates ACh receptor and keeps channel open
  • very short acting
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10
Q

ambenzonium

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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11
Q

donepezil

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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12
Q

echothiophate

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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13
Q

edrophonium

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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14
Q

galantamine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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15
Q

neostigmine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

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16
Q

physostigmine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

17
Q

pyridostigmine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

18
Q

rivastigmine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

19
Q

tacrine

A
  • AChE inhibitor

- used for myasthenia gravis, dementia

20
Q

atropine

A

-Muscarinic ACh receptor blocker

21
Q

glycopyrrolate

A

-antimuscarinic

22
Q

pralidoxime

A
  • AChE regenerator

- used to treat the toxic inhibition of AChE inhibitors like organophosphates

23
Q

baclofen

A
  • GABAb agonist
  • spasmolytic drug
  • results in inhibition of excitatory neurotransmitter release
24
Q

carisprodol

A
  • MOA unknown

- spasmolytic, anxiolytic

25
Q

cyclobenzaprine

A
  • MOA unknown

- spasmolytic, drowsiness

26
Q

diazepam

A
  • GABAa receptor agonist
  • spasmolytic drug
  • increases effect of GABA on its receptor
27
Q

tizanidine

A
  • α2 agonist

- spasmolytic drug

28
Q

dantrolene

A
  • blocks Ca+ release from SR by blocking RYR

- used to treat malignant hyperthermia

29
Q

botox

A
  • cleaves the VAMP and blocks vesicle fusion to presynaptic membrane
  • spasmolytic agent
30
Q

glucocorticoids

A
  • MS treatment

- immunosuppressive

31
Q

glatiramer acetate

A
  • MS treatment

- activate T lymphocyte suppressor cells

32
Q

IFN-β

A
  • MS treatment

- inhibit T lymphocyte adhesion to BBB

33
Q

mitoxantrone

A
  • MS treatment
  • antineoplastic
  • intercalates into DNA and causes strand breaks and cross links

Various Pharm (44 decks)

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