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Various Pharm > Drugs for Asthma and COPD > Flashcards

Drugs for Asthma and COPD Flashcards

1
Q

Albuterol

A
  • SABA (Short Acting β2 Agonist): reverses the bronchoconstriction of asthma by relaxing airway smooth muscle
  • risk of headache, dizziness, dry mouth, cough
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2
Q

Terbutaline

A
  • SABA (Short Acting β2 Agonist): reverses the bronchoconstriction of asthma by relaxing airway smooth muscle
  • used for treatment or prophylaxis of bronchospasm associated with asthma
  • only available as SubQ
  • risk of headache, nausea, tachycardia, and palpitations.
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3
Q

Metaproterenol

A
  • SABA (Short Acting β2 Agonist): reverses the bronchoconstriction of asthma by relaxing airway smooth muscle
  • used for bronchial asthma and for reversible bronchospasm
  • risk of CV effects, paradoxical bronchospasm
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4
Q

Pirbuterol

A
  • SABA (Short Acting β2 Agonist): reverses the bronchoconstriction of asthma by relaxing airway smooth muscle
  • used for reversal of bronchospasm in pts 12 years or older
  • risk of CV effects on pulse or BP
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5
Q

Levalbuterol

A
  • SABA (Short Acting β2 Agonist): reverses the bronchoconstriction of asthma by relaxing airway smooth muscle
  • Used in treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease.
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6
Q

Beclomethasone

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 5 years of age and older
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • risk of adrenal dysfunction
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7
Q

Budesonide

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 6 years of age and older
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • do NOT use as treatment for status asthmaticus, or severe episodes of asthma
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8
Q

Ciclesonide

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 6 years of age and older
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • do NOT use for relief of acute bronchospasm
  • less likely to cause candidiasis
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9
Q

Flunisolide

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 6 years of age and older
  • may replace oral CS
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • do NOT use as treatment for status asthmaticus, or severe episodes of asthma
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10
Q

Fluticasone

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 4 years of age and older
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • risk or oral candidiasis
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11
Q

Mometasone

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy in patients 4 years of age and older
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • do NOT use in pts with sensitivity to milk proteins, as treatment for status asthmaticus, or severe episodes of asthma
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12
Q

Triamcinolone

A
  • Inhaled corticosteroid
  • Used as maintenance treatment for asthma and as prophylactic therapy
  • reduce eosinophils in airway and sputum, and inhibit transcription of inflammatory proteins
  • May replace Oral CS
  • do NOT use as treatment for status asthmaticus, or severe episodes of asthma
  • risk of adrenal dysfunction
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13
Q

Prednisone

A
  • Oral Corticosteroid
  • Used as an anti-inflammatory or immunosuppressive agent and in endocrine conditions
  • May lead to hypothalamic-pituitary-adrenal (HPA) axis suppression
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14
Q

Fomoterol

A
  • LABA (Long Acting β2 Agonist)
  • Treatment of asthma in patients ≥5 years as an ADD-ON to a long-term asthma control medication such as an inhaled corticosteroid.
  • Maintenance treatment of bronchoconstriction in patients with COPD
  • risk of asthma-related deaths and asthma-related hospitalizations.
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15
Q

Salmeterol

A
  • LABA (Long Acting β2 Agonist)
  • Treatment of asthma in patients aged 4 years and older. Prevention of exercise-induced bronchospasm (EIB) in patients aged 4 years and older.
  • Also, maintenance treatment of bronchospasm associated with COPD
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16
Q

Indacaterol and Vilanterol

A
  • LABA (Long Acting β2 Agonist)

- Used to treat breathing problems caused by COPD

17
Q

Olodaterol

A
  • LABA (Long Acting β2 Agonist)

- Used in the long-term, once-daily maintenance bronchodilator treatment of airflow obstruction in patients with COPD

18
Q

Atropine

A
  • Muscarinic receptor antagonist
  • When the recurrent use of atropine is essential in patients with coronary artery disease, the total dose should be restricted to 2 to 3 mg to avoid the detrimental effects of atropine-induced tachycardia on myocardial oxygen demand.
19
Q

Ipratroprium

A
  • Muscarinic receptor antagonist
  • Used as a bronchodilator for maintenance treatment of bronchospasm associated w/ COPD
  • poorly absorbed after aerosol administration and is therefore relatively free of systemic atropine-like effects.
20
Q

Tiotropium

A
  • Muscarinic receptor antagonist

- maintenance treatment of bronchospasm associated with COPD

21
Q

Aclidinium

A
  • Muscarinic receptor antagonist

- maintenance treatment of bronchospasm associated with COPD

22
Q

Theophylline

A
  • Methylxanthine

- Smooth muscle relaxation (bronchodilation) and suppression of the response of the airways to stimuli

23
Q

Montelukast

A
  • Leukotriene Receptor (CysLT1) Antagonist
  • treat allergies and prevent asthma attacks.
  • NOT indicated for use in the reversal of bronchospasm in acute asthma attacks, including status asthmaticus.
24
Q

Zafirlukast

A
  • Leukotriene Receptor (CysLT1) Antagonist
  • Selective and competitive receptor antagonist of leukotriene D4 and E4
  • Prescribed for the prophylaxis and chronic treatment of asthma in adults and children 5 years of age and older
  • risk of hepatotoxicity
25
Q

Zileuton

A
  • Inhibitor of 5-lipoxygenase and thus inhibits leukotriene
  • Used as a prophylaxis and chronic treatment of asthma in adults and children 12 years of age and older and not used to treat an acute asthma attack.
  • Do not use in active liver dz
26
Q

Omalizumab

A
  • anti-IgE antibody
  • used for moderate to severe persistent asthma in patients 6 years of age and older with a positive skin test or in vitro reactivity to a perennial aeroallergen and symptoms that are inadequately controlled with inhaled corticosteroids.
  • also used for chronic idiopathic urticaria
  • risk of anaphylaxis

Various Pharm (44 decks)

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