Antenatal and Perinatal Pharm Flashcards
1
Q
misoprostol
A
- induction of labor
- synthetic PGE1 analog
- causes uterine contractions
- keep ductus arteriosus patent
- can also be used for termination, or for cervical ripening
- risk of n/v, chills and shivering, abnormal uterine contraction
2
Q
dinoprostone
A
- induction of labor
- synthetic PGE2 analog
- induces uterine contractions and promotes cervical ripening
- given as a cervical insert, or vaginal gel
- can cause fever that is unresponsive to NSAIDS
3
Q
carboprost
A
- induction of labor
- synthetic PG F2α analog
- causes uterine contractions
- can be used for termination, and post-partum hemostasis
- risk of pulmonary edema d/t vasoconstriction, fevers and chills, choking sensation and gagging
4
Q
oxytocin
A
- induction of labor
- increases force, frequency and duration of uterine contractions
- also used for post-partum hemostasis
- do not use if fetal lungs are undeveloped, or if cervix is not softened
- risk of hyponatremia
5
Q
ergot alkaloids
A
- induction of labor
- stimulates adrenergic, dopaminergic, and serotonergic receptors to cause extended uterine contractions
- given for post-partum hemostasis
- risk of st. anthony’s fire
6
Q
alprostadil
A
- maintains patent ductus arteriosus
- synthetic PGE1
7
Q
indomethacin
A
- closes ductus arteriosus
- tocolytic
- risk of gerd, gastritis, and emesis
8
Q
ibuprofen
A
-closes ductus arteriosus
9
Q
cortisol
A
-corticosteroid
10
Q
betmethasone
A
-fluorinated corticosteroid
11
Q
dexamethasone
A
-fluorinated corticosteroid
12
Q
erythromycin ointment
A
-antibiotic used to prevent gonococcal eye infections in newborns
13
Q
vitamin k
A
-prevents bleeding
14
Q
hepatitis B vaccine
A
-given w/in 24 hr
15
Q
terbutaline
A
- β2 agonist that acts as a tocolytic
- increases cAMP and leads to K+ channel mediated hyperpolarization
- risk of hypotension, SOB, tachycardia, arrhythmias
