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Various Pharm > Antipsychotic Drugs > Flashcards

Antipsychotic Drugs Flashcards

1
Q

chlorpromazine

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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2
Q

fluphenazine

A
  • first generation antipsychotic
  • available as LAIA
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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3
Q

perphenazine

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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4
Q

thioridazine

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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5
Q

trifluoperazine

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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6
Q

haloperidol

A
  • first generation antipsychotic
  • available as LAIA
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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7
Q

loxapine

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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8
Q

molindone

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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9
Q

pimozide

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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10
Q

thiothixene

A
  • first generation antipsychotic
  • block D2, 5-ht, muscarinic, α1, and H1 receptors
  • risk of EPS, and hyperprolactinemia
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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11
Q

iloperodone

A
  • second generation antipsychotic
  • block 5-HT2A and D2 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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12
Q

lurasidone

A
  • second generation antipsychotic
  • block 5-HT2A and D2 receptors
  • ALSO a partial 5HT-1A agonist
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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13
Q

paliperidone

A
  • second generation antipsychotic (metabolite of risperidone)
  • available as LAIA
  • block 5-HT2A and D2 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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14
Q

risperidone

A
  • second generation antipsychotic
  • available as LAIA
  • block 5-HT2A and D2 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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15
Q

ziprasidone

A
  • second generation antipsychotic
  • block 5-HT2A and D2 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
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16
Q

aripiprazole

A
  • second generation antipsychotic
  • available as LAIA
  • partial agonist of 5-HT1A and D1 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
17
Q

brexpiprazole

A
  • second generation antipsychotic
  • partial agonist of 5-HT1A and D1 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
18
Q

cariprazine

A
  • second generation antipsychotic
  • block 5-HT2A and D2 receptors AND partial agonist of 5-HT1A and D1 receptors
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
19
Q

lumateperone

A
  • second generation antipsychotic
  • multiple receptor agonism
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
20
Q

asenapine

A
  • second generation antipsychotic
  • multiple receptor agonism
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
21
Q

clozapine

A
  • second generation antipsychotic
  • multiple receptor agonism
  • risk of AGRANULOCYTOSIS, NMS, weight gain, metabolic syndrome, QT prolongation, stroke
  • used for treatment resistant psychosis or multiple suicide attempts
22
Q

olanzapine

A
  • second generation antipsychotic
  • available as LAIA
  • multiple receptor agonism
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
23
Q

quetipine

A
  • second generation antipsychotic
  • multiple receptor agonism
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
24
Q

pimavanserine

A
  • second generation antipsychotic
  • used for PARKINSONS PSYCHOSIS
  • risk of NMS, weight gain, metabolic syndrome, QT prolongation, stroke
25
Q

valbenazine

A
  • selective VMAT2 inhibitor

- treatment of tardive dyskinesia side effect

26
Q

deutetrabenazine

A
  • selective VMAT2 inhibitor

- treatment of tardive dyskinesia side effect

Various Pharm (44 decks)

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