Section 2: Notes Flashcards
the lateral ventricle covers the ___ and ___
hypothalamus and thalamus
cognitive deficits signal what part of the brain?
forebrain
what is the striatum?
caudate, putamen
what is the basal gang.?
caudate, putamen, globus pallidus, substantia nigra, and subthalamus
what part of the brain is the basal gang. located in?
forebrain (gp, caudate, putamen are)
what structures are in the limbic system?
amygdala, anterior part of cingulate gyrus, orbital and medial prefrontal gyri, ventral parts of basal gang., hippocampus, parts of thalamus
what causes the cavity in the ventral lateral surface of the anterior horn of the lateral ventricle
head of the caudate
a hollow on the ventral medial surface of the inferior horn is produced by the____.
hippocampus.
the hole piercing the third ventricle made by the ____
massa intermedia
the “beak” of the third ventricle is surrounded by the ____
hypothalamus
he medial surface of the posterior horn normally abuts the ____.
calcarine sulcus
the _____ lies above the fourth ventricle
cerebellum
what forms the floor of the 4th ventricle?
the contiunation of the tegmentum into the pons
what does the blood brain barrier protect the brain from?
- sever flucations in ionic concentrantions - toxic compounds - circulating hormones and NT released in other parts of the body
The actual locus of the BBB is the capillary endothelium which is specialized by having what three things?
1) tight junctions between capillary endothelial cells 2) few endocytotic vesicles for intracellular transport 3) a high number of mitochondria indicative of high levels of oxidative metabolism.
what 3 methods is entry into the brain achieved?
- diffusion (lipid solube) 2. facilitative and energy depend. transport (water sol. like glucose and a.a.) 3. ion channels
how do molecules get to the blood from the brain
a reverse pump in astroglia transpots lipophilic molecules back out
how do some whole moelcules get into the blood brain barrier (like ymphocytes and macrophages)
a mechanism that opens tight junctions (implicated in disease with MS lymphocytes and HIV infected macrophages)
what are 3 examples in which the blood brain barrier breaks down
brain tumor, bacterial invasion, ischemia
ischemic directly damages cells ____ pumps
NA and K
what are some of the causes of edema with stroke?
ischemia alters na and k channels ionic influx causes cells to swell
csf is in equilibrium with
brain extracellular fluid
what is the total volume of csf? how much is made per day?
140 ml is total volume, 500 ml made per day so a lot of turn over (3-4x)
what secretes csf?
choroid plexus