Reticular Formation and Cerebellum (3) Flashcards
the reticular formation is the central core of the brainstem and extends into the cerebrum as the _____
hypothalamus
From medial to lateral what are the 3 longitudinal zones of the RF ?
R and L Median zone - Raphe
Medial Zone - Paramedian
lateral zone (largestt) Zone
what zone of the RF houses most of the ascending and descending neural tract projections
Medial or paramedian zone
what part of the brainstem would you find the lateral zone of the RF
rostral medulla and caudal pons
what zone of the RF is involved with cranial nerve reflexes and visceral functions
Lateral zone
what are the 2 reticulospinal tracts of the RF, and where could they be found in the brainstem
- medial reticulospinal tract - pons
- lateral reticulospinal tract - medulla
The RF and its reticulospinal tracts are involved with what functions
- regulate spinal motor neurons
- influence spinal motor neurons directly
- regulate spinal reflexes
the reticulospinal tract neurons of the RF recieve input from where ?
cerebral cortex
basal ganglia
substantia nigra … (multiple locations)
the RF is known to be a “pattern generator”, what does this mean
Controls/coordinates rhythmic motor patterns
- gaze centers (midbrain and pons)
- mastication (pons)
- locomotion (pons)
- medulla vital center
the RF is involved with controlling rhythmic motor patterns, and one area of control is the Medulla “vital center” which controls what ?
- respiration
- heart rate
- swallowing/vomiting
what is bruxism and what are the theories for what causes this ?
tooth grinding cuz jaw muscles are co-contracted at night
- Peripheral theory - jaw muscles constantly trying to reach occlusion
- Central theory - sleep related neural dysfunction
what role can the RF play in pain pathways
Suppress or facilitate pain (wounded soldiers keep fighting)
where is the central location that is involved with RF pain supress system
periaqueductal grey (PAG)
what zone of the RF would fibers carrying pain infortmation be found ?
Raphe (nucleus magnus) —–> then to posterior horn of spinal cord
where would you find opiate receptors in the RF
- PAG
- raphe
- posterior horn of spinal cord
What is the RF role in autonomic reflex circuitry
controls visceral information and responds accordingly to environmental changes
(similar to pattern generators in motor control)
what part of the brainstem is involved with the RF involvment in arousal
midbrain and pons
-sends info to thalamus then cortex and heightens arousal
the RF control of maintaining consciousness is better known as what system
Ascending reticular activating system (ARAS)
damage to what part of the brainstem could result in prolonged coma
bilateral damage to midbrain would damage ARAS of RF
T/F ARAS has a role in the sleep-wake cycles
True
what nuerochemicals involved with the RF are produced in the brainstem
norepinephrine (NE)
dopamine (DA)
serotonin
what neurochemicals involved with the RF are produced in the hypothalamus
histamine containing neurons
what neurochemical partly involved with the RF is produced in the telencephalon
acetylcholine
norepinephrine is made by _______ neurons which are located where ?
noradrenergic neurons
- Rostral pons (locus ceruleus) ***
- medulla (solitary nucleus)
sensory info that stimulates the locus ceruleus neurons cause what ?
production of NE (increase arousal and anticipation)
-releases into cortex, trigeminal spinal nucleus, spinal cord
reduced locus ceruleus activity (reduced levels of NE) causes what
clinical depression
increased activity of the locus ceruleus (increase NE) could cause
panic disorder
dopamine is produced by ________ neurons located where
dopaminergic neurons in the midbrain
- substantia nigra
- ventral tegmental area
what tract degenerates in people with parkinsons disease
nigrostriatal tract (substantia nigra to striatum) -involved with motor activity from DA
what are the components of the striatum and what neurochemical has projections through here
caudate and putamen
-dopaminergic projections
what is the major source of DA
Ventral tegmental area
what are the 2 tracts of the Ventral Tegmental Area
Mesolimbic tract - to limbic system
Mesocortical tract - to frontal cortex