Respiratory Physiology - Control of Ventilation - Acid base balance Flashcards

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1
Q

What is acid based balance controlled by?

A

renal and respiratory system

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2
Q

What is acid based balance?

A

controlling the pH of extracellular fluid

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3
Q

What is the normal pH of extracellular fluid?

A

pH 7.4

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4
Q

What do the peripheral chemoR respond to?

A

increasing plasma [H+], often originating from CO2 also plasma.

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5
Q

What happens to [H+], when plasma pH falls?

A

[H+] increases

simulating ventilation

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6
Q

What happens when there is an increase of [H+] in the plasma?

A

increase in ventilation

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7
Q

Describe the relationship between ventilation and plasma [H+] (graph)

A

linear

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8
Q

What happens when ventilation increases?

A

acidosis ([H+] increases)

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9
Q

What happens when plasma hydrogen ion concentration decreases?

A

increase in pH

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10
Q

What happens when to ventilation when hydrogen ion conc falls?

A

inhibition of ventilation

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11
Q

How would you describe a fall in hydrogen ion conc?

A

alkalosis

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12
Q

What is the relationship between the ventilation and plasma hydrogen ion concentration?

A

a change in the hydrogen ion conc of plasma will chnage ventilation

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13
Q

Wy does ventilation change when hydrogen ion conc changes?

A

try and restore the normal hydrogen ion conc

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14
Q

What is metabolic acidosis?

A

increase in hydrogen ion conc in plasma for a reason that is not a change in respiratory function

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15
Q

What would cause an increase in hydrogen ion concentration in plasma?

What receptors would be stimulated

A

lactic acid production

stimulate peripheral chemoR

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16
Q

When metabolic acidosis occurs, and you increase ventilation, what way will the line of the graph move?

A

move to left

17
Q

How does increasing ventilation decrease hydrogen ion conc?

A

drives the equation to the left and blow off more CO2, and reduce H+ conc.

negative feedback loop

18
Q

Why would you want to inhibit ventilation when hydrogen ion ocnc falls?

A

retain CO2 and drive equation to the right and increase hydrogen ion conc and compensate for the fall in plasma hydrogen ion conc

19
Q

What is respiratory alkilosis?

A

increasing ventilation (hyperventilate)

blow off CO2 and move equation to the left and reduce the H+ plasma

20
Q

What do most respiratory disease arise from?

A

decreased ventilation

21
Q

What is respiratory acidosis?

A

decreased ventilation, retain CO2, drive equation to the right and build up of H+ in the plasma and acidosis

22
Q

What is the equation of CO2 to H+?

A
23
Q

Is CO2 capable of changing ECF pH?

A

yes

24
Q

Does hypoventilation retain of blow off CO2?

A

CO2 retention

25
Q

Does hyperventilation blow off or retain CO2?

A

CO2 blow off

26
Q

What does this equation tell you?

A

pH is proportionate to bicarbonate and CO2

27
Q

What is HCO3 controlled by?

A

kindneys

28
Q

What is CO2 managed by?

A

lungs

29
Q

What is the equation for acid based balance?

A
30
Q

In this equation, what happens if CO2 increases?

A

pH decreases

acidic

31
Q

In this equation, what happens if HCO3 increases?

A

pH increases

more alkaline