Respiratory Physiology - Control of Ventilation - Acid base balance Flashcards
What is acid based balance controlled by?
renal and respiratory system
What is acid based balance?
controlling the pH of extracellular fluid
What is the normal pH of extracellular fluid?
pH 7.4
What do the peripheral chemoR respond to?
increasing plasma [H+], often originating from CO2 also plasma.
What happens to [H+], when plasma pH falls?
[H+] increases
simulating ventilation
What happens when there is an increase of [H+] in the plasma?
increase in ventilation
Describe the relationship between ventilation and plasma [H+] (graph)
linear
What happens when ventilation increases?
acidosis ([H+] increases)
What happens when plasma hydrogen ion concentration decreases?
increase in pH
What happens when to ventilation when hydrogen ion conc falls?
inhibition of ventilation
How would you describe a fall in hydrogen ion conc?
alkalosis
What is the relationship between the ventilation and plasma hydrogen ion concentration?
a change in the hydrogen ion conc of plasma will chnage ventilation
Wy does ventilation change when hydrogen ion conc changes?
try and restore the normal hydrogen ion conc
What is metabolic acidosis?
increase in hydrogen ion conc in plasma for a reason that is not a change in respiratory function
What would cause an increase in hydrogen ion concentration in plasma?
What receptors would be stimulated
lactic acid production
stimulate peripheral chemoR