quiz 6 agonists antagonists ad autnomic Flashcards

1
Q

variety of what embedded in membrane of cells around the body

A

receptors

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2
Q

what are receptors looking for

A

a specific signal or signals which will cause them to do certain things

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3
Q

agonist

A

any chemical that binds to a receptor and activates it

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4
Q

antagonists

A

some chemicals that bind to the same receptors but do not turn them on, instead they sit on the receptor and block them from being activated

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5
Q

agonist alone

A

full activation

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6
Q

agonist and antagonist

A

less activation

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7
Q

antagonist alone

A

no activation

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8
Q

what does the autonomic nervous system do

A

control the body’s involuntary muscles

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9
Q

2 parts of the autonomic nervous system

A

parasympathetic (PSNS)

Sympathetic (SNS) nervous systems

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10
Q

PSNS and SNS are constant what

A

in battle, one trying to overtake or outweighs the other

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11
Q

sympathetic nervous system response

A

fight or flight

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12
Q

two hormones released in sympathetic nervous system

A

epinephrine (adrenaline) and norepinephrine

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13
Q

sympathetic NS is going to do what things necessary to survive interaction with sabertooth tiger

A
  • heart rate/ volume up
  • airway dilates
  • blood pressure up
  • glycogenolysis in liver
  • pupils dilate
  • respiratory rate up
  • blood shunted away from GI
  • blood shunted towards muscles
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14
Q

glycogenolysis

A

breaks won glycogen into glucose

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15
Q

adrenergic receptor

A

any receptor where epinephrine or norepinephrine can bind

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16
Q

adrenergic receptors come in

A

variety of shapes and sizes and do different things, but are all part of the sympathetic nervous system

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17
Q

subtypes of adrenergic receptors

A

alpha-1, alpha-2, beta-1, beta-2, beta-3

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18
Q

parasympathetic nervous

A

rest or digest (feed or breed)

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19
Q

main hormone involved in parasympathetic nervous system

A

Acetylcholine (ACh)

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20
Q

parasympathetic nervous system will not help you

A

fight saber tooth tiger

21
Q

what does the parasympathetic nervous system do

22
Q

what does SLUDGE-PM

A
Salivation (drooling)
Lacrimation (tearing up)
Urination (peeing)
Diaphoresis (sweating)
GI upset (diarrhea)
Emesis (vomiting)
Priapism (erection)
Miosis (pupils constrict)
23
Q

speed of parasympathetic response

A

much slower than sympathetic

24
Q

receptors activate when acetylcholine binds to them

A

cholinergic receptors

25
two types of cholinergic receptors
muscarinic receptors and nicotinic receptors
26
subtypes of muscarinic and nicotinic receptors
M1 through M5 muscarinic receptors and N1 and N2 nicotinic receptors
27
activation of cholinergic receptors causes
some of the SLUDGE-PM response to happen
28
what happens when acetylcholine binds to M2 receptors in heart
slow heart rate
29
what does atropine do
blocks M2 receptors, stopping ACh from binding there
30
what type of chemical is atropine
antagonist
31
who would give atropine to
people whose hearts you want to go faster
32
beta-1 receptors
located mostly on the heart, norepinephrine and epinephrine can bind to it
33
who do you give beta blockers to
people whose hearts you don't want to beat too fast , (people with heart diseaseproblem) could stop heart attack
34
what happens when norepinephrine and epinephrine bind to beta -1 receptors
the heart beats harder and faster
35
what is the suffix for a beta blocker
olol
36
what are beta blockers
drugs that block beta-1 receptors from binding norepinephrine and epinephrine
37
epinephrine also binds to which receptors located around the body
beta-2 receptors
38
what happens when epinephrine binds to beta-2 receptors
the muscles in the bronchi (in lungs) relax, which allows the bronchi to expand
39
EpiPEns do wha
inject epinephrine straight into the bloodstream
40
what would epipens do to BP/ HR
Heart rate gets faster and blood pressure raises
41
what would epipens do in anaphylaxis
it allows airways to relax and get bigger
42
PSNS and SNS run through what
CNS (spinal cord)
43
severe neck/spine injury can wipe out what
sympathetic and parasympathetic nervous systems
44
PSNS is much slower in what than SNS
being wiped out by severe neck/spine injury
45
PSNS system takes longer to disappear because
hormones linger around
46
what is the result of PSNS taking longer than SNS to dissappear
PSNS is full force for a few units
47
neck/spine trauma often indicated by
priapism
48
people hanged to death often experience
death erection when neck breaks in execution because of PSNS overload