quiz 3 types of proteins Flashcards

1
Q

what are the types of proteins

A

enzymes, signaling proteins, transport proteins, structural proteins, regulatory proteins

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2
Q

are all enzyme proteins

A

yes

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3
Q

what is the function of enzymes

A

to speed up chemical reactions and lower activation energy

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4
Q

are enzymes used up

A

no

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5
Q

what is a substrate

A

molecule(s) that initially attach to enzyme

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6
Q

what is the product

A

molecule(s) released from the enzyme

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7
Q

what is the active site

A

the place where the enzyme and substrate attach

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8
Q

are there different enzymes for different chemical reactions

A

yes

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9
Q

what is an enzyme-substrate complex

A

the enzyme an substrate attached together

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10
Q

whats the equation for enzyme use

A

E + S becomes ES becomes EP becomes E + P

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11
Q

what are the six examples of enzymes

A

salivary amylase, pepsin, DNA ligase, DNA helicase, DNA polymerase, ATP synthase

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12
Q

what does salivary amylase do

A

it is an enzyme in saliva that breaks down starches into sugar

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13
Q

what does pepsin do

A

it is found in the stomach, breaks down proteins into peptides, then into amino acids

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14
Q

what does DNA ligase do

A

joins DNA strands together

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15
Q

what does DNA helicase do

A

uncoils and separates DNA strands

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16
Q

what does DNA polymerase do

A

builds DNA molecules by sticking nucleotides together

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17
Q

what does ATP synthase do

A

enzyme that turns ADP into ATP

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18
Q

do enzymes have a very specific shape

A

yes

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19
Q

what are enzymes highly sensitive to

A

changes in pH or temperature

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20
Q

can slight changes cause shape changes

A

yes

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21
Q

changes in pH an temperature cause

A

denaturation

22
Q

example of important signaling protein

A

insulin

23
Q

what happens when cells in your pancreas detect glucose in your blood

A

insulin is released into your bloodstream

24
Q

what does insulin bind to

A

insulin receptors on cells

25
Q

does insulin enter the cell

A

no

26
Q

*what happens when insulin bounds to receptors

A

triggers a cascade that leads cells to be able to take in glucose from the blood and converts it into ATP

27
Q

why is insulin so important

A

without it, cells cannot take in glucose

28
Q

what is the problem with oxygen

A

it is not very soluble in water or blood, but must travel through it to get to tissues

29
Q

what does hemoglobin do

A

found in red blood cells, transports proteins, and transports oxygen to body cells

30
Q

how much oxygen can hemoglobin hold

A

each oxygen can hold 4 O2 molecules

31
Q

*****how does hemoglobin know when to “let go” of oxygen molecules

A

the Bohr effect: when tissues work hard they release CO2, CO2 reacts with water, forming H+ molecules and making the blood more acidic. When blood is more acidic, hemoglobin has a lower affinity for oxygen, making it more prone to release it

32
Q

what are two other ways to say structural proteins

A

fibrous proteins or scleroproteins

33
Q

how are structural proteins different in shape than other body proteins

A

they aren’t globular

34
Q

three examples of scleroproteins

A

collagen, elastin, keratin

35
Q

what is the most abundant protein in the body

A

collagen at 30%

36
Q

what is the function of collagen

A

take up the extracellular space in the body, and is the main connective tissue

37
Q

are their many sub-types of collagen

A

yes

38
Q

what is the cause of scurvy

A

a lack of vitamin C

39
Q

why is vitamin C necessary

A

for two enzymes, prolyl hydroxylase , lysyl hydroxylase , to link one collagen protein to another, without vitamin C, collagen fibers do not function properly

40
Q

what is the result of scurvy

A

Result: fatigue, feeling “out of it”, limb pain
Later, swollen gums, shortness of breath, easily bruised skin
Finally, seizures, jaundice, edema, and death

41
Q

what do regulatory proteins do

A

cause genes to be turned up or down in response to certain events

42
Q

how do regulatory proteins accomplish their goal

A

usually by binding to DNA or RNA

43
Q

what is p53 often called

A

the guardian of the genome

44
Q

what are the two main functions of p53

A
  • to stop the cell cycle if DNA damage is detected

- cause the cell to enter apoptosis if DNA damage not fixed

45
Q

what are found in virtually all cancer cells

A

Mutant or inactivated p53 genes

46
Q

what cells must do to become cancerous

A

inactivate or circumvent p53

47
Q

when is p53 inactive

A

usually present but when bound to mdm2

48
Q

what happens when DNA damage is detected in a cell

A

p53 separates from mdm2`

49
Q

what happens when p53 is alone

A

it will bind to a region of DNA and cause the genes the coding for the protein p21 to be expressed at higher rates

50
Q

what does p21 do

A

stops the cell cycle from continuing until the DNA damage has been repaired

51
Q

what is apoptosis

A

programmed cell death

52
Q

what happens if the dna damage is not repaired

A

p53 will lead to apoptosis by turning on other genes