Prac 2: Haematology Cases

Question 1

What is polychromasia evidence of?

Answer 1

Regeneration

Question 2

What does a polychromatophil look like?

Answer 2

Large, pale blue

Question 3

What does a metarubricyte look like?

Answer 3

Like a lymphocyte but dark

Question 4

What is the most likely cause of leucopaenia/lymphopaenia in a cat?

Answer 4

Stress

Question 5

What ongoing process can cause thrombocytosis?

Answer 5

Inflammation

Question 6

What does serum amyloid A measure?

Answer 6

Sensitive marker of inflammation

Question 7

What are some differentials for eosinophilia?

Answer 7

Parasites, allergy/hypersensitivity, paraneoplastic, eosinophilic inflammatory disorders (enteritis, bronchopneumopathy), Addisons

Question 8

Which kind of haemolysis are spherocytes a feature of?

Answer 8

Extravascular, immune mediated

Question 9

What does Coombs test look for?

Answer 9

Autoimmune haemolytic anaemia

Question 10

What are the two differentials for lymphocytosis?

Answer 10

Lymphoproliferative disease, chronic inflammation, Cushings, Ehrlichia

Question 11

What value can Heinz bodies artificially elevate?

Answer 11

MCHC

Question 12

Which stain for Heinz bodies?

Answer 12

Methylene blue

Question 13

What process can also cause MCHC elevation?

Answer 13

Haemolysis, either in vitro or in vivo

Question 14

What processes can monocytosis suggest?

Answer 14

Ongoing inflammation or stress

Question 15

What conditition can D-dimer be used to assess?

Answer 15

DIC

Question 16

What is the most likely cause of iron deficiency in an older animal?

Answer 16

Chronic haemorrhage e.g. GI bleed, parasites, urine loss

Question 17

Which tests can you do to confirm iron deficiency?

Answer 17

Serum iron and total iron binding capacity (marker of transferrin)

Question 18

What is on process that can cause increased platelet consumption?

Answer 18

Inflammation

Question 19

What are two causes of basophilia?

Answer 19

Parasitic or allergic disease