14: Fluid Cytology Flashcards

1
Q

What is cellularity of pleural fluid?

A

Low cellularity

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2
Q

What cells do pleural fluids contain?

A

Mesthelial cells

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3
Q

Which kind of effusions are unilateral and compartmentalised?

A

Mild

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4
Q

Which kind of effusions are bilateral?

A

Abundant

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5
Q

What do you use EDTA tubes for?

A

Cell evaluation and counting

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6
Q

What do you use plain tubes for?

A

Protein, cholesterol, triglyceride

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7
Q

Whihc kind of fluids deteriorate quickly?

A

Washes, effusions, synovial fluids

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8
Q

What is a transudate?

A

From pressure/oncotic changes, low protein/cells, yellow to colourless

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9
Q

What is a modified transudate?

A

More cells/protein, clear or slightly turbid

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10
Q

What is a septic or non-septic exudate?

A

High protein, turbid, blood-tinged

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11
Q

What might you see if your transudate is pleural or from a cat?

A

Some macrophages and neutrophils or lymphocytes

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12
Q

Which cells would you find in a modified transudate from the abdomen?

A

50% macrophage, 50% neutrophils

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13
Q

What does a septic exudate contain?

A

Bacteria

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14
Q

What does a non-septic exudate contain?

A

More than 50% neutrophils

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15
Q

What are effusions like in FIP?

A

High protein, macrophage, and neutrophil, non-septic

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16
Q

What is the cholesterol:triglyceride ratio in chylous effusions?

A

Below 1 (more triglyceride and less cholesterol than serum)

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17
Q

What else do you find in a haemorrhagic effusion?

A

Macrophages to phagocytose RBCs

18
Q

In which species is uroabdomen common?

A

Foals/male pigs

19
Q

What causes bile peritonitis?

A

Ruptured/leaking bile duct

20
Q

What colour is bile?

A

Yellow with orange crystals

21
Q

Which kind of fluid do neoplasias cause?

A

Modified transudate with abnormal cells (cell-rich)

22
Q

Which cells can look like tumour cells in fluid?

A

Mesothelial

23
Q

Which tube for a synovial fluid sample?

A

EDTA, plain or culture medium

24
Q

What’s the usual amount of synovial fluid you can get?

A

Less than 0.5ml

25
Why is synovial fluid viscous?
Hyaluronic acid
26
How can you take a cell count from synovial fluid?
Cells show windrowing due to the viscosity
27
When do cells in the synovial fluid not show windrowing?
If too watery (pathological)
28
What % of cells in synovial fluid are neutrophils?
5-10%
29
Which are the mononuclear cells seen in synovial fluid?
Most - synoviocytes or macrophages
30
In which species is immune-mediated inflammatory joint disease common?
dog
31
In which species is immune-mediated inflammatory joint disease rare?
Horse
32
How do you indentify inflammatory joint disease from synovial fluid?
Increased neutrophils
33
What can you see in haemarthrosis fluid?
Bright orange haematoidin crystals and dark brown haemosiderin (iron) deposits within macrophages
34
What is mononuclear arthropathy?
DJD
35
What can DJD be secondary to?
Osteochondrosis, joint instability, trauma
36
Which cells can you see in DJD?
Mononulcear cells and sometimes "joint mice"
37
What kind of cells do you see in immune-mediated arthritis?
Non-degenerate neutrophils, increased lymphocytes and plasma cells
38
What are four causes of infectious arthritis?
Bacterial, fungal (puncture wounds), protozoa, rickettsia (Ehrlichia)
39
What cells do you see in infectious arthritis?
High cell count, degenerate neutrophils
40
Where are bacteria commonly found in infectious arthritis?
Lining