23: Analysing data

Question 1

What is Bence Jones proteinuria?

Answer 1

Light chain fragments of Igs small enough to get through glomerular barrier (in myelomas)

Question 2

What can IMHA be secondary to?

Answer 2

Infection, drugs, neoplasia, SLE

Question 3

Which markers for B lymphocytes?

Answer 3

CD21 and CD79a

Question 4

Which markers for T lymphocytes?

Answer 4

CD3

Question 5

Which markers for histiocytes?

Answer 5

CD14

Question 6

What can you not use to assess liver function in jaundiced animals?

Answer 6

Bile acids - excreted the same way as bilirubin so if bilirubin is high then bile acids will be high too even if hepatocyte function is normal

Question 7

What do you use instead of ALT in horses?

Answer 7

GLDH

Question 8

What do you use instead of ALP in horses?

Answer 8

GGT

Question 9

Why do dogs with PSS get ammonium biurate crystals in the urine?

Answer 9

Cannot metabolise urea

Question 10

What is the advantage of cPLI over DGGR?

Answer 10

Just as sensitive and specific, but there is a cPLI snap

Question 11

Is Cushing’s usually PDH or ADH?

Answer 11

PDH

Question 12

What causes PDH?

Answer 12

excess ACTH secretion and bilateral adrenal hyperplasia (microadenomas)

Question 13

What causes ADH?

Answer 13

adenomas and carcinomas

Question 14

Until what age is GGT high in foals?

Answer 14

2-4 weeks

Question 15

Why do you get alkalosis and paradoxical aciduria in displaced abomasum?

Answer 15

Sequestration of HCL and lack of Cl in urine