POXVIRIDAE Flashcards
Genus
- Chordopox- and
- (Entomopoxvirinae) = insects
(Pock=scar)
Morphology
Enveloped
dsDNA (Linear)
Complex capsid
Resistance
Usually Good Stable at room temp Sensitive to: - Heat detergents - Formaldehyde - Oxidizing agents
Replication
Baltimore I
Replicate in the cytoplasm
Use viral enzymes
Biological Properties
- Stenoxen
- Orthopox, Parapox = Zoonosis(effect human)
- Airborn
- Contact
Arthropods (Vector bourne)
Antigenic Properties
STRONG antigens - long immunity
- exept parapox virus
Diagnosis
Clinical signs
Isolation by egg inoculation
- chorion allantoic membrane
EM
Genus Chordopoxviridae viruses
- Orthopox virus
- Parapox virus
- Avipox virus (Birds)
- Capripox virus (Capra=Goat)
- Leoripox virus (lepus=rabbit)
- Suipox virus
- Yatapoxvirus
- Molluscipoxvirus
Genus Chordopoxviridae viruses
Ortopox virus
(Ortho=Real)
1. Cowpox- Cattle skin lesions. Pass from Rodents->Cats->Human
2- Buffalopox- Asia
- Camelpox
- Mice skin lesions. Loss of legs
- Variola - “small pox” - skin, pneumonia
- Vaccinia- Mutant cowpox… vaccination against variola.
- MonkeyPox
Genus Chordopoxviridae viruses
2. Parapox virus
- Pseudo-cowpox.
- Teat lesions and scabs in milking cows - Bovine Popular Stomatitis.
- Lesions on muzzle and in the oral cavity of cows. (Zoonosis) - Contagious ecthyma
- Lambs: mouth, lip
- Humans: skin, lip, eye - Sealpox
- Squirel parapox virus
- Skin, lesions: red squirrels
Genus Chordopoxviridae viruses
3. Avipox
(Avis=birds)
Skin: mucosal
scabs, pneumonia
- Fowl-, Canary-, Pidgeon-, Turkeypox..
- Transmitted by arthropods
Genus Chordopoxviridae viruses
4. Capripox virus (Capra=Goat)
Sheep-pox - Notifable
Goat-pox
Lumpy skin disease
Genus Chordopoxviridae viruses
5. Leoripox virus (lepus=rabbit)
- Myxomatosis in rabbit-
- Pneumonia
- lesions w/in skin: Trans-> Mosquitos - Hare-Fibroma virus causes tumors
- Shope-Fibroma virus - tumors in RABBITS
Genus Chordopoxviridae viruses
6. Suipoxvirus
Swinepox virus-
- Occurs worldwide and causes skin disease.
- Transmitted - lice
Genus Chordopoxviridae viruses
7. Yatapoxvirus
- Yabapox- Monkey tumours
2. Tanapox- Skin lesions