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Virology FINAL nr2 > HEPADNAVIRIDAE > Flashcards

HEPADNAVIRIDAE Flashcards

1
Q

Genus

A

(Hepar - DNA)

  1. Orthohepadna or
  2. Avihepadna
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2
Q

Morphology

A

Enveloped
Icosahedral capsid
Ss/dsDNA (Circular)

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3
Q

Resistance

A 
Weak
PH-low
Intolerant to:
- Acid
- Detergent
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4
Q

Replication

A
  • Baltimore VI
  • Replication with reverse transcriptase
  • Cytoplasm at first but when it becomes DNA it enters the nucleus
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5
Q

Biological properties

A 
Stenoxenous
Transmitted by:
- Blood
- Sexual contact
- Close contact
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6
Q

Antigen properties

A

HBsAg is the surface antigen of the hepatitis B virus (Protective role)

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7
Q

Diagnosis

A

ELISA
(Enzyme-linked immuno-sorbent assay )
- direct and
- indirect.

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8
Q

Hepadnaviridae viruses

A
  1. Othohepadna:
    - Human hepatitis B
    - Hepatocarcinoma = Livercancer (40%)
  2. Avihepadna:
    - Duck hepatitis (Asia)
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Virology FINAL nr2 (35 decks)

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