FLAVIVIRIDAE Flashcards
1
Q
Genus
A
(Flavus - Yellow)
- Flavi
- Pesti
- Hepaci
2
Q
Morphology
A
Enveloped
+ssRNA Genome
3
Q
Resistance
A
Weak - Enveloped!
4
Q
Biological properties
A
- Baltimore IV - Single polyprotein precursors
- CEP - Non or untypical
(flavivirus -> Hemagglutination) - Flavivirus = arbovirus->zoonosis (rash, fever)
5
Q
Antigenic properties
A
Good antigens
Cross reaction within genera
6
Q
Diagnosis
A
Clinical signs: IF, PCR
Serology - ELISA, IF, PRNT
7
Q
Flavivirus genome
A
- Tick borne encephalitis - Human and goats
- Louping ill - Sheep meningoencephalitis
- Yellow fewer!!
- Dengue fewer (1-4) - Africa > Dengue hamerrorhagic shock
8
Q
Pestivirus genome
A
- Classical swine fever - Hog Cholera
- More controllable than ASF
- Ecological losses - High mortality
- Haemorrhagic fever - Bovine Viral Diarrhoea - BVD
- Calf diarrhoea
- Mucosal disease (MD) - fatal - Sheep fetopathy - “Hairy shaker” lamb
9
Q
Hepacivirus (Hepar C)
A
Hepatitis C virus
- Cirrhosis (skrumplever)
- No vacsine