FLAVIVIRIDAE Flashcards

1
Q

Genus

A

(Flavus - Yellow)

  1. Flavi
  2. Pesti
  3. Hepaci
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2
Q

Morphology

A

Enveloped

+ssRNA Genome

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3
Q

Resistance

A

Weak - Enveloped!

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4
Q

Biological properties

A
  • Baltimore IV - Single polyprotein precursors
  • CEP - Non or untypical
    (flavivirus -> Hemagglutination)
  • Flavivirus = arbovirus->zoonosis (rash, fever)
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5
Q

Antigenic properties

A

Good antigens

Cross reaction within genera

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6
Q

Diagnosis

A

Clinical signs: IF, PCR

Serology - ELISA, IF, PRNT

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7
Q

Flavivirus genome

A
  1. Tick borne encephalitis - Human and goats
  2. Louping ill - Sheep meningoencephalitis
  3. Yellow fewer!!
  4. Dengue fewer (1-4) - Africa > Dengue hamerrorhagic shock
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8
Q

Pestivirus genome

A
  1. Classical swine fever - Hog Cholera
    - More controllable than ASF
    - Ecological losses - High mortality
    - Haemorrhagic fever
  2. Bovine Viral Diarrhoea - BVD
    - Calf diarrhoea
    - Mucosal disease (MD) - fatal
  3. Sheep fetopathy - “Hairy shaker” lamb
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9
Q

Hepacivirus (Hepar C)

A

Hepatitis C virus

  • Cirrhosis (skrumplever)
  • No vacsine
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