ASFARVIRIDAE

Question 1

Genus

Answer 1

• Asfivirus
  AFRICAN SWINE FEVER
• Fever, haemorrhage in skin, tissues and organs. High mortality rate.

Question 2

Morphology

Answer 2

Enveloped
Icosahedral capsid
dsDNA (Linear)

Question 3

Resistance

Answer 3

Weak
Can live for months in raw pork meat
Destroyed by:
- Heating
- Lipid solvent
- Disinfectants

Question 4

Replication

Answer 4

Baltimore I

• Multiplication in the cytoplasm of the host.
• Released by budding from the host cell or with the disintegration of host cell

Question 5

Biological properties

Answer 5

Stenoxen
Multiplied in lymphoid cells
Transmission - Ticks

Question 6

Antigenic properties

Answer 6

• No vaccines available
• Hidden protective antigen and no neutralizing antibodies in recovered animal sera
• Persistent infection

Question 7

Diagnosis

Answer 7

• Clinical signs:

Classical swine fever - similar symptoms
= Need lab conformation (IF or ELISA)

• Isolation in a buffy coat culture.