BIRNAVIRIDAE Flashcards
1
Q
Genus
A
(bi-RNA)
- Avibirna
- Aquabirna
2
Q
Morphology
A
Non-enveloped
Icosahedral capsid
Segmented (2) dsRNA
3
Q
Resistance
A
Strong
Resistant to chloroform and ether.
Heat: 56°C for 1hour
4
Q
Replication
A
- Baltimore III
- In the cytoplasm of host cells
(involving a virion-associated RNA dependant RNA polymerase) - Uses Viral transcriptase as well
5
Q
Biological properties
A
Propgates only in species specific tissue cultures = hard to isolate
6
Q
Antigenic Properties
A
Good Antigens
No cross reactions.
7
Q
Diagnosis
A
Isolation
Clinical signs
IF
EM
8
Q
Avirnavirus:
A
Gumboro disease -Infectious bursal disease:
- Multiplies in Bursa Fabricii in the chicken
- causes immuno-suppression
9
Q
Aquabirnavirus
A
Salmonidae -Infectious pancreatic necrosis: