Porphyrias Flashcards
1
Q
What are porphyrias?
A
They are disorders with defective enzymes, leading to defective heme synthesis (heme + globin=hemoglobin)
2
Q
What is one porphyria that affects skin?
A
Porphyria cutanea tarda—defective enzyme in heme synthesis pathway leads to photosensitivity with skin blistering; familial PCT involves defective urobilinogen decarboxylase (heme synthesis enzyme)
