Disseminated intravascular coagulation (DIC)

Question 1

What is MOA of Disseminated intravascular coagulation (DIC)?

Answer 1

Get schistocytes

Question 2

What do you see on blood smear?

Answer 2

HELLP syndrome= manifestation of severe preeclamspia (hypertension after 20 weeks with either proteinuria or end-organ dysfunction; usually seen in last 3 months of pregnancy or shortly after childbirth; affects about 15% of women with pre-eclampsia, or eclampsia)🡪 can progress to DIC, placental abruption, or kidney failure

• Hemolysis of RBC’s (lactate dehydrogenase will be elevated)
• Elevated Liver enzymes (AST, ALT)
• Low platelets

Question 3

Sx?

Answer 3

Other HELLP sx: epigastric pain, right upper abdom quadrant pain, headache, visual issues, nausea, vomiting, backache, htn