Merkel cell carcinoma Flashcards
1
Q
What is Merkel cell carcinoma?
A
Tumor of merkel cells, which are found in stratum basale of epidermis of skin, and are neuroendocrine cells that function in detecting light touch.
Physician Task: Applying Foundational Science Concepts (108 decks)
- Anterior versus posterior pituitary gland products
- Embryonic precursor of anterior pituitary
- Vibrio Cholera causes for diarrhea.
- Organs that carry out gluconeogenesis
- Cytokines that recruit different cell types
- Pro-inflammatory cytokines
- Cytokines that stimulate cachexia--weight loss, muscle atrophy, and fatigue during chronic disease (eg, cancer, AIDS, heart failure, COPD)
- Anti-inflammatory cytokines
- Common infectious causes of granulomas
- Common noninfectious causes of granulomas
- Major types of antigen-presenting cells
- Major dermatome landmarks
- Spinal nerve roots of genitofemoral, femoral, and sciatic nerves
- Common cause of painful bulging anal mass
- Th1 and Th2 cell function
- Cells and cytokines involved in granuloma formation
- Type 2 pneumocyte location
- Effect on ADH, Central blood volume, and ANP after 20 min cold water submersion
- Poison ivy rash (to urushiol) relation to HSR
- Male/female genital analogs
- Female paramesonephric/Mullerian duct derivatives
- Male mesonephric/Wolffian duct derivatives
- Major biochem deficiencies and symptoms
- Whipple disease and sx
- Tumor causing microbes
- MOA and toxicities of chemo and immunosuppressive agents
- MOA of most common immunosuppressants
- Common B-cell immune-deficiency syndromes
- Common T-cell immune-def. syndromes
- Common combined B-cell and T-cell disorders
- Most common phagocyte immunodeficiencies
- Pt’s without/with decreased B-cells and their infection risk
- Porphyrias
- Mechanisms and enzymes involved in Osteogenesis imperfecta
- Results of UMN lesions
- Types of hypercholesterolemia
- Fibrates
- Nicotinic acid=Niacin=B3
- Ezetime
- Cholestyramine, cholestipol, and colesevlam
- Statins
- PCKS9 inhibitors
- Treatment for mild cholesterol gallstones
- Hypertriglyceridemia
- Heart chamber closest to esophagus
- Heart chamber closest to front of chest
- SA node
- Differences between types of Mycobacterium leprae
- Coagulation cascade
- Bleeding time
- Fibrinogen factor
- Disseminated intravascular coagulation (DIC)
- Congenital adrenal enzyme deficiencies
- The Brain
- Brain fill in the blank
- Corticospinal tract fiber origins
- Lobes and cortexes
- MLF lesion
- Differences between Contralatral hemiballismus versus Huntington’s disease
- Respiratory compensation
- Tricuspid valve murmur
- E.Coli virulence factors
- Superantigens
- Cerebral hematomas
- Type of hematoma
- Skeletal muscle activation MOA
- Hemochromatosis sx and lab sx
- Image question
- Bullous pemphigoid and pemphigus vulgaris
- Nitrosamines, aflatoxin, and glue inhalation toxicity
- Splenic infarct
- Hypocalcemia and hypercalcemia
- Hypokalemia and hyperkalemia
- Enzyme test for gram-positive bacteria
- Uteran and ovarian arteries
- Aledronate
- Heparin and warfarin
- Physiology of ejaculation
- Parasympathetic nerve supply to hindgut
- Cavernous sinus
- Skin cancer
- Skin cancer 2
- Skin cancer 3
- Skin cancer appearances
- Merkel cell carcinoma
- Skin condition
- Actinic keratosis
- Ankylosing spondylitis
- Image question 2
- Tactile fremitus
- Most common paraneoplastic syndrome associated with small cell lung cancer
- Thyroid-binding globulin production
- Pulmonary capillary wedge pressure=pulmonary artery occlusion pressure
- Estrogen and liver failure
- Aortic stenosis and aortic regurgitation/insufficiency
- Crystals and polarized light
- Ichen sclerosis
- K+ sparing diuretics
- Loop diuretics
- Carbonic anhydrase inhibitors
- Polysaccharide antigen vaccine
- IV saline concentration
- hCG function in men
- Clinical trail stages
- Clinical trail question
- Upper motor neuron lesions and hyperreflexia/hyporeflexia
- Metastasizing of carcinomas and sarcomas
- Fungin antifungal mechanism
