Nicotinic acid=Niacin=B3

Question 1

What is Nicotinic acid=Niacin=B3?

Answer 1

• most effective drug to increase HDL; 1) decreases hepatic VLDL secretion and 2) inhibits hormone-sensitive lipase in adipose tissue🡪decreased release of FFA’s into serum
• Major effects: increase HDL and decrease LDL; minor effect: decrease triglycerides
• Fish oil can also be used to slightly increase HDL
• Give with aspirin to decrease flushing