Cytokines that stimulate cachexia--weight loss, muscle atrophy, and fatigue during chronic disease (eg, cancer, AIDS, heart failure, COPD)

Question 1

What cytokines stimulate cachexia–weight loss, muscle atrophy, and fatigue that occur in chronic disease (eg, cancer, AIDS, heart failure, COPD)?

Answer 1

Mediated by TNF-α , IFN-γ , IL-1, and IL-6.