Pharmacology for respiratory

Question 1

Diphenylhdramine

Answer 1

H1 blocker (1st gen)

Question 2

Dimenhydrinate

Answer 2

H1 blocker (1st gen)

Question 3

Chlorpheniramine

Answer 3

H1 blocker (1st gen)

Question 4

Loratidine

Answer 4

H1 blocker (2nd gen)

Question 5

Fexofenadine

Answer 5

H1 blocker (2nd gen)

Question 6

Desloratidine

Answer 6

H1 blocker (2nd gen)

Question 7

Cetrizine

Answer 7

H1 blocker (2nd gen)

Question 8

Guafenesin

Answer 8

thins respiratory secretions, expectorant

Question 9

N-acetylcsteine

Answer 9

loosens mucous plugs in CF pt

Question 10

Dextromethorphan

Answer 10

Antitussive, antagonizes NMDA glutamate receptors

Question 11

Pseudoephedrine

Answer 11

sympathomimetic a agonist- nasal decongestant

Question 12

Phenylephrine

Answer 12

sympathomimetic a agonist- nasal decongestant

Question 13

salmeterol

Answer 13

long-acting B2 agonist

Question 14

formoterol

Answer 14

long-acting B2 agonist

Question 15

Theophylline

Answer 15

methylxanthine, bronchodilation via inhib phosphdiesterase

Question 16

ipratropium

Answer 16

muscarinic antag, prevent bronchoconstriction

Question 17

beclomethasone

Answer 17

corticosteroid, NFkB/cytokine inhib

Question 18

fluticasone

Answer 18

corticosteroid, NFkB/cytokine inhib

Question 19

Montelukast

Answer 19

blocks leukotriene receptor, esp good for aspirin-induced asthma

Question 20

Fluticasone

Answer 20

blocks leukotriene receptor, esp good for aspirin-induced asthma

Question 21

Zileuton

Answer 21

5-lipoxygenase pathway inhib (arachidonic acid to leuktriene)

Question 22

omalizumab

Answer 22

monoclonal anti-IgE antibody

Question 23

Bosentan

Answer 23

treats pulm arterial hypertension; antagonizes endothelin-1 receptor