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Step 1 > Pharmacology for Repro > Flashcards

Pharmacology for Repro Flashcards

1
Q

Leuprolide

A

GnRH analog

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2
Q

Clomiphene

A

SERM:

Antagonist of estrogen receptors in hypothalamus

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3
Q

What is clomiphene used to treat?

A

infertility due to anovulation (eg PCOS)

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4
Q

Tamoxifen

A

SERM:
antagonist breast tissue
agonist uterus, bone

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5
Q

Raloxifene

A

SERM:
Agonist bone
antagonist uterus

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6
Q

What SERM is used to treat osteoporosis

A

raloxifene

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7
Q

Anastrozole

A

aromatase inhibitor

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8
Q

Exemestane

A

aromatase inhibitor

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9
Q

What are aromatase inhibitors used for?

A

postmenopausal women with breast cancer

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10
Q

What is the action of oral contraceptives?

A

inhibit LH/FSH, prevent estrogen surge

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11
Q

Terbutaline

A

b2 agonist, decr uterin contraction

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12
Q

Danazol

A

partial agonist of androgen receptors

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13
Q

What is danazol used to treat

A

endometriosis, hereditary angioedema

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14
Q

What does flutamide inhibit?

A

nonsteroidal competitive inhibitor of testosterone receptor

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15
Q

What is the anti-androgen function of ketoconazole

A

inhibits 17-20 desmolase

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16
Q

What is the anti-androgen function of spironolactone

A

inhibits steroid binding, 17a-hydroxylase, inhibits 17-20 desmolase

17
Q

What are ketoconazole and spironolactone used to treat?

A

PCOS

18
Q

Tamsolusin

A

a1antagonist- treat BPH, selective

19
Q

What drug is contraindicated for patients taking sildenafil

A

nitrates

Step 1 (34 decks)

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